Evidence map›Paper›PMID 42621020›Full record

SynthesisFrontiers in neurology2026

Effects of qigong exercise on post-stroke cognitive impairment: a systematic review and meta-analysis of randomized controlled trials.

Chengning Song, Huanxin Xie, Haiyan Li, Bo Lei, Bin Luo, Weijuan Gu, Huimin Wang, Yanxian Zou

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in Frontiers in neurology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Chengning SongShenzhen Fuyong People's Hospital, Shenzhen, China.
Huanxin XieShenzhen Traditional Chinese Medicine Hospital, Shenzhen, China.
Haiyan LiShenzhen Fuyong People's Hospital, Shenzhen, China.
Bo LeiShenzhen Fuyong People's Hospital, Shenzhen, China.
Bin LuoShenzhen Fuyong People's Hospital, Shenzhen, China.
Weijuan GuShenzhen Fuyong People's Hospital, Shenzhen, China.
Huimin WangShenzhen Fuyong People's Hospital, Shenzhen, China.
Yanxian ZouShenzhen Fuyong People's Hospital, Shenzhen, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Post-stroke cognitive impairment is common and negatively affects functional recovery and quality of life. Qigong is widely used in stroke rehabilitation, but its effects on cognitive outcomes remain uncertain. Objectives: To evaluate the effects of qigong exercise on cognitive function after stroke and to explore whether effects vary across qigong types (Baduanjin, Yijinjing, Liuzijue, and Dao-yin-type exercises). Methods: We systematically searched seven databases from inception to January 2026: PubMed (87 records), Embase (112), Web of Science (106), the Cochrane Library (82), CNKI (224), Wanfang (230), and VIP (147). We included randomized controlled trials in people after stroke that compared qigong with control conditions, including the same usual rehabilitation alone, health education, sham exercise, or other non-qigong interventions. Two reviewers independently screened studies, extracted data, and assessed risk of bias. The primary outcome was cognitive function measured by the Montreal Cognitive Assessment; the Mini-Mental State Examination was a supplementary outcome. Post-intervention mean and standard deviation values were preferentially extracted, and standard deviations were derived from standard errors when needed. Meta-analyses were performed in Review Manager 5.4.1 using mean differences with 95% confidence intervals under a random-effects model. Heterogeneity was assessed using Results: Sixteen RCTs were included; 14 reported MoCA and 2 reported MMSE. Qigong improved MoCA versus control (random-effects model: MD = 1.87, 95% CI 1.33-2.40; Conclusion: Current evidence suggests that qigong improves cognitive function after stroke, with a significant increase in MoCA scores overall. Benefits were observed for Baduanjin and Liuzijue, whereas Yijinjing showed no statistically significant improvement. Two Dao-yin trials reported improved MMSE but with substantial heterogeneity. Further well-designed clinical trials are warranted to confirm these findings and clarify effects across qigong types and outcomes. Systematic review registration: Registered in PROSPERO (CRD420261320472).

Indexed as

Cognitive DysfunctionQigongStrokeStroke RehabilitationHumansRandomized Controlled Trials as TopicBaduanjinLiuzijuemeta-analysisMontreal Cognitive Assessmentpost-stroke cognitive impairmentqigongstrokeYijinjing

Identifiers

PMID42621020
PMCPMC13485980

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.