ArticleSmart molecules : open access2026
Rational design of a lipophilic β-galactosidase-responsive near-infrared probe for in vivo imaging of cellular senescence.
Article in Smart molecules : open access, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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16 authors.
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Abstract
Senescence-associated β-galactosidase (SA-β-gal) is a key biomarker of cellular senescence and has been demonstrated to be a major driver of various age-related diseases and tumor resistance. However, noninvasive in vivo imaging of SA-β-gal remains challenging due to the poor membrane permeability of existing probes, their reliance on intratumoral injection, and limited blood-brain barrier (BBB) permeability. This study reports a novel, rationally designed near-infrared (NIR) fluorescent probe,
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