Evidence map›Paper›PMID 42620955›Full record

ArticleJCPP advances2026

Childhood adversity and psychotic-like experiences in adolescence: Investigating a pathway via disrupted pubertal and grey matter development.

Megan Thomas, Sarah Whittle, Elizabeth M Haris, Vanessa L Cropley

Abstract read
In one paragraph

Article in JCPP advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Megan ThomasOrygen The National Centre of Excellence in Youth Mental Health Parkville Victoria Australia.ORCID https://orcid.org/0000-0002-1112-950X
Sarah WhittleCentre for Youth Mental Health University of Melbourne Parkville Victoria Australia.
Elizabeth M HarisOrygen The National Centre of Excellence in Youth Mental Health Parkville Victoria Australia.
Vanessa L CropleyOrygen The National Centre of Excellence in Youth Mental Health Parkville Victoria Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Childhood adversity increases psychosis risk, but the biological mechanisms responsible remain elusive. A possible but underexplored pathway involves altered pubertal and grey matter (GM) development. Methods: In youth from the Adolescent Brain Cognitive Development study ( Results: Associations were found between all adversity types and greater PLEs, of which most were mediated by earlier pubertal timing and/or slower tempo. Mediation effects tended to be stronger in females, and for socioeconomic deprivation pathways. Results did not support the presence of serial mediation pathways from adversity to PLEs via puberty-related GM variation. Conclusion: Findings suggest that disruption to pubertal development may contribute to the link between adversity and psychosis risk, but not by altering GM development. Investigating puberty alongside alternative biological systems may help contextualise our findings.

Indexed as

adversityneurodevelopmentpsychosispuberty

Identifiers

PMID42620955
PMCPMC13487410

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.