Evidence map›Paper›PMID 42620947›Full record

ArticleFrontiers in aging neuroscience2026

Impact of exercise on cognitive efficiency in older adults with subjective memory complaints: a randomized clinical trial.

Gustavo O Silva, Melanie Clark, Nicola T Lautenschlager, Hannah J Thomas, Kurt J Smith, Barbara A Maslen, Kay L Cox, Carmela F Pestell, Philip N Ainslie, Howard H Carter and 2 more

Abstract read
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In one paragraph

Article in Frontiers in aging neuroscience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Gustavo O Silva *School of Human Sciences (Exercise and Sport Science), The University of Western Australia, Perth, WA, Australia.
Melanie Clark *Neurosciences Institute, Perron Institute, Nedlands, WA, Australia.
Nicola T LautenschlagerDepartment of Psychiatry, The University of Melbourne, Parkville, VIC, Australia.
Hannah J ThomasSchool of Human Sciences (Exercise and Sport Science), The University of Western Australia, Perth, WA, Australia.
Kurt J SmithSchool of Human Sciences (Exercise and Sport Science), The University of Western Australia, Perth, WA, Australia.
Barbara A MaslenSchool of Human Sciences (Exercise and Sport Science), The University of Western Australia, Perth, WA, Australia.
Kay L CoxSchool of Human Sciences (Exercise and Sport Science), The University of Western Australia, Perth, WA, Australia.
Carmela F PestellSchool of Psychological Science, University of Western Australia, Perth, WA, Australia.
Philip N AinslieCentre for Heart, Lung and Vascular Health, School of Health, and Exercise Science, University of British Columbia, Kelowna, BC, Canada.
Howard H CarterSchool of Human Sciences (Exercise and Sport Science), The University of Western Australia, Perth, WA, Australia.
Louise H NaylorSchool of Human Sciences (Exercise and Sport Science), The University of Western Australia, Perth, WA, Australia.
Daniel J GreenSchool of Human Sciences (Exercise and Sport Science), The University of Western Australia, Perth, WA, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Cerebrovascular dysfunction may contribute to cognitive impairment in older adults. Exercise is recommended for preventing cerebrovascular health and cognition; however, it remains unclear whether cognitive changes are related to changes in cerebrovascular function. Thus, this study aimed to examine whether exercise-induced changes in cognition and subjective memory complaints are associated with changes in cerebral blood velocity. Methods: This study is a randomized controlled trial that included 72 sedentary older adults with memory complaints (age = 62 ± 7, 19 [26%♂]). Participants were randomized to a land-walking (LW), water-walking (WW), or control group (C). Exercise groups ( Results: TMT-B improved in the WW group compared to C ( Conclusion: Improvements in neuropsychological status and subjective memory were associated with reduced resting MCAv following exercise training. These exploratory associations suggest that variability in cerebrovascular responses may relate to cognitive responses; however, without consistent group-level effects, findings should be interpreted cautiously and do not imply causality. Clinical trials registration: https://www.anzctr.org.au/, ACTRN12614000017628.

Indexed as

cerebral blood flowcerebrovascular functioncognitioncognitive ageingexercise

Identifiers

PMID42620947
PMCPMC13485977

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.