Evidence map›Paper›PMID 42620931›Full record

ArticleHuman mutation2026

A Pathogenic

Xu Linglong, Gao Jingwen, Zhu Wenting, Lu Nina, Ding Xiaoxiao, Zhao Lei, Zhou Siyun, Cai Zihao, Zhong Zhengyang, Zhu Bo and 6 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Human mutation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. A PathogenicHuman mutation · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Xu LinglongDepartment of Hematology, Taizhou Central Hospital (Taizhou University Hospital), School of Medicine, Taizhou University, Taizhou, Zhejiang, China, tzc.edu.cn.ORCID https://orcid.org/0000-0003-4496-6571
Gao JingwenZhejiang Key Laboratory of New Drug Development for Central Nervous System Diseases, Taizhou University, Taizhou, Zhejiang, China, tzc.edu.cn.ORCID https://orcid.org/0009-0005-1737-2091
Zhu WentingDepartment of Hematology, Taizhou Central Hospital (Taizhou University Hospital), School of Medicine, Taizhou University, Taizhou, Zhejiang, China, tzc.edu.cn.ORCID https://orcid.org/0009-0003-5251-4644
Lu NinaDepartment of Hematology, Taizhou Central Hospital (Taizhou University Hospital), School of Medicine, Taizhou University, Taizhou, Zhejiang, China, tzc.edu.cn.ORCID https://orcid.org/0009-0007-3031-1183
Ding XiaoxiaoDepartment of Hematology, Taizhou Central Hospital (Taizhou University Hospital), School of Medicine, Taizhou University, Taizhou, Zhejiang, China, tzc.edu.cn.ORCID https://orcid.org/0009-0009-5648-8563
Zhao LeiDepartment of Laboratory Medicine, Taizhou Central Hospital (Taizhou University Hospital), School of Medicine, Taizhou University, Taizhou, Zhejiang, China, tzc.edu.cn.ORCID https://orcid.org/0009-0003-9971-4491
Zhou SiyunDepartment of Hematology, Taizhou Central Hospital (Taizhou University Hospital), School of Medicine, Taizhou University, Taizhou, Zhejiang, China, tzc.edu.cn.ORCID https://orcid.org/0000-0002-0532-9441
Cai ZihaoDepartment of Hematology, Taizhou Central Hospital (Taizhou University Hospital), School of Medicine, Taizhou University, Taizhou, Zhejiang, China, tzc.edu.cn.ORCID https://orcid.org/0009-0003-5502-7673
Zhong ZhengyangDepartment of Hematology, Taizhou Central Hospital (Taizhou University Hospital), School of Medicine, Taizhou University, Taizhou, Zhejiang, China, tzc.edu.cn.ORCID https://orcid.org/0000-0002-8555-6109
Zhu BoDepartment of Hematology, Taizhou Central Hospital (Taizhou University Hospital), School of Medicine, Taizhou University, Taizhou, Zhejiang, China, tzc.edu.cn.ORCID https://orcid.org/0000-0002-9689-1228
Chen SaiDepartment of Hematology, Taizhou Central Hospital (Taizhou University Hospital), School of Medicine, Taizhou University, Taizhou, Zhejiang, China, tzc.edu.cn.ORCID https://orcid.org/0009-0002-7228-8288
Guo YanrongDepartment of Hematology, Taizhou Central Hospital (Taizhou University Hospital), School of Medicine, Taizhou University, Taizhou, Zhejiang, China, tzc.edu.cn.ORCID https://orcid.org/0009-0000-2768-6813
Chen JianlinDepartment of Hematology, Taizhou Central Hospital (Taizhou University Hospital), School of Medicine, Taizhou University, Taizhou, Zhejiang, China, tzc.edu.cn.ORCID https://orcid.org/0009-0000-4733-6351
Chen JieZhejiang Key Laboratory of New Drug Development for Central Nervous System Diseases, Taizhou University, Taizhou, Zhejiang, China, tzc.edu.cn.ORCID https://orcid.org/0000-0001-7962-0840
Ding XiaofeiZhejiang Key Laboratory of New Drug Development for Central Nervous System Diseases, Taizhou University, Taizhou, Zhejiang, China, tzc.edu.cn.ORCID https://orcid.org/0000-0002-0820-4652
Chen GuangDepartment of Hematology, Taizhou Central Hospital (Taizhou University Hospital), School of Medicine, Taizhou University, Taizhou, Zhejiang, China, tzc.edu.cn.ORCID https://orcid.org/0000-0002-1885-7374

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hereditary spherocytosis (HS) is a common inherited hemolytic anemia characterized by spherical erythrocytes, splenomegaly, and increased osmotic fragility, with

Indexed as

AnkyrinsMutationSpectrinSpherocytosis, HereditaryAnimalsDisease Models, AnimalErythrocytesFemaleGenetic Predisposition to DiseaseHumansMaleMicePhenotypeProtein BindingANK1 protein, humanAnk1 protein, mouseAnkyrinsSpectrinSPTB protein, humanANK1 c.5096G>A mutationankyrin-1 (ANK1)hereditary spherocytosis (HS)β-spectrin

Identifiers

PMID42620931
PMCPMC13487465

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.