Evidence map›Paper›PMID 42620918›Full record

ArticleFrontiers in human neuroscience2026

A pilot study of spinal reflex modulation during immersive virtual reality exposure in humans.

Maxim Baltin, Anna Shulman, Margarita Nikulina, Elizaveta Vinogradova, Dmitry Onishchenko, Diana Sabirova, Tatyana Baltina

Abstract read
In one paragraph

Article in Frontiers in human neuroscience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Maxim BaltinResearch Center for Genetics and Life Sciences, Sirius University of Science and Technology, Sirius Federal Territory, Russia.
Anna ShulmanResearch Laboratory of Mechanobiology, Institute of Fundamental Medicine and Biology, Kazan Federal University, Kazan, Russia.
Margarita NikulinaResearch Center for Genetics and Life Sciences, Sirius University of Science and Technology, Sirius Federal Territory, Russia.
Elizaveta VinogradovaResearch Center for Genetics and Life Sciences, Sirius University of Science and Technology, Sirius Federal Territory, Russia.
Dmitry OnishchenkoResearch Center for Genetics and Life Sciences, Sirius University of Science and Technology, Sirius Federal Territory, Russia.
Diana SabirovaResearch Center for Genetics and Life Sciences, Sirius University of Science and Technology, Sirius Federal Territory, Russia.
Tatyana BaltinaResearch Laboratory of Mechanobiology, Institute of Fundamental Medicine and Biology, Kazan Federal University, Kazan, Russia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The integration of virtual reality (VR) technologies into clinical rehabilitation and diagnostics is rapidly expanding, yet the neurophysiological mechanisms of their influence on spinal motor circuits remain poorly understood. This pilot study assessed the modulation of spinal reflex excitability during exposure to specific immersive audiovisual stimuli delivered via a virtual reality headset, compared to classical neuromodulation paradigm. Materials and methods: Twenty-one healthy volunteers completed a within-subject design. The H-reflex and M-response parameters of the Results: H-reflex thresholds remained stable across all conditions ( Conclusion: These preliminary results suggest that the specific immersive audiovisual stimuli tested in this study can selectively modulate spinal reflex excitability via central descending pathways rather than peripheral mechanisms. The results of this preliminary research provide a foundation for the design of future investigations.

Indexed as

H-reflexJendrassik maneuverM-responseneuromodulationsegmental excitabilityspinal reflexesvirtual reality

Identifiers

PMID42620918
PMCPMC13485893

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.