ArticleJournal of vascular surgery cases and innovative techniques2026
A case of surgical excision of cyanoacrylate-filled vein due to delayed-type hypersensitivity reaction following cyanoacrylate closure for lower-extremity varicose veins.
Article in Journal of vascular surgery cases and innovative techniques, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Hypersensitivity reaction (HSR) is a known adverse event after cyanoacrylate closure (CAC) for varicose veins, and surgical excision is rarely required. We report the case of surgical excision of a cyanoacrylate-filled vein due to HSR after CAC. A 68-year-old woman developed erythema and swelling of the thigh 5 days after CAC of the great saphenous vein. Symptoms persisted despite antiallergic medication, and HSR was clinically suspected. At the patient's request, surgical excision of the treated vein was performed. Histopathological examination showed dense infiltration of CD4-positive T cells. Surgical excision may be considered in selected cases of refractory HSR after CAC.
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