Evidence map›Paper›PMID 42620736›Full record

ArticleFrontiers in cell and developmental biology2026

SLight-Net: a lightweight spectral-layer aware network for retinal disease detection based on optical coherence tomography.

Yixiang Yao, Jin Hong, Rongli Zhang, Junhua Hu, Libin Lu, Peixin Tan, Zhongbiao Xu, Shuhua Luo

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Article in Frontiers in cell and developmental biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Yixiang YaoSchool of Information Engineering, Nanchang University, Nanchang, China.
Jin HongSchool of Information Engineering, Nanchang University, Nanchang, China.
Rongli ZhangDepartment of Diagnostic Radiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pok Fu Lam, Hong Kong, China.
Junhua HuState Key Laboratory of Water Cycle and Water Security, China Institute of Water Resources and Hydropower Research, Beijing, China.
Libin LuSchool of Information Engineering, Wuhan College, Wuhan, China.
Peixin TanDepartment of Radiotherapy, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Southern Medical University, Guangzhou, China.
Zhongbiao XuDepartment of Radiotherapy, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Southern Medical University, Guangzhou, China.
Shuhua LuoGanzhou Key Laboratory of Medical Imaging and Artificial Intelligence, Medical Imaging Center, Ganzhou Institute of Medical Imaging, Ganzhou People's Hospital, The Affiliated Ganzhou Hospital of Nanchang University, Ganzhou Hospital-Nanfang Hospital, Southern Medical University, Ganzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Retinal diseases are a major cause of preventable visual impairment, and optical coherence tomography (OCT) provides high-resolution cross-sectional imaging for retinal assessment. However, reliable interpretation of OCT B-scans remains challenging because of speckle noise, subtle layer-wise changes, and visually similar pathological patterns. Methods: We propose SLight-Net, a lightweight spectral-layer aware network for retinal OCT classification. The model is built on a compact three-stage convolutional backbone and incorporates two OCT-specific modules. The Frequency-Aware Spectral-Spatial Encoder (FASE) integrates local convolution, dilated contextual modeling, and learnable spectral modulation to capture multi-scale structural and frequency-aware retinal features. The Retinal Layer Depth Attention (RLDA) module further introduces a depth-direction anatomical prior to recalibrate feature responses along retinal layers. Deep supervision and exponential moving-average weight updating are used to improve optimization stability. Results: On the OCT-C8 benchmark, SLight-Net achieves 98.21% classification accuracy with only 1.204M parameters. Additional evaluation on OCT2017 shows 99.30% accuracy, suggesting that the model maintains stable performance under a different class setting while remaining compact. Conclusion: These findings indicate that OCT-specific spectral and layer-aware priors can support efficient retinal disease classification without relying on large generic backbones, providing a practical basis for lightweight computer-aided OCT analysis.

Indexed as

anatomically informed priorslightweight neural networkoptical coherence tomographyretinal OCT classificationspectral-spatial attention

Identifiers

PMID42620736
PMCPMC13486991

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.