ArticleFrontiers in nutrition2026
Gene-diet interaction between
Article in Frontiers in nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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7 authors.
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Abstract
Background: Precision nutrition seeks genotype-informed dietary guidance. We examined the associations of Methods: We analyzed 9,263 adults from the Taiwan Biobank with rs3764261 genotype data and available HDL-C measurements. Rs3764261 genotypes were obtained from whole-genome genotyping using the TWBv2.0 Affymetrix SNP array, with quality control based on Hardy-Weinberg equilibrium, minor allele frequency, and call-rate thresholds. Vegetarian diet status was defined using questionnaire data (being vegetarian throughout the day for >6 months). Associations were evaluated using multiple linear regression models, adjusting for relevant covariates and testing the rs3764261 × vegetarian-diet interaction. Results: A total of 9,263 adults were included, comprising 8,330 non-vegetarians and 933 vegetarians. Vegetarians had significantly lower mean HDL-C than non-vegetarians (53.190 vs. 56.031 mg/dL, Conclusion: Rs3764261 modified the association between vegetarian diet status and HDL-C levels, supporting evidence for gene-diet interactions in precision nutrition approaches to lipid risk management.
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