Evidence map›Paper›PMID 42620683›Full record

ArticleFrontiers in big data2026

Differentiated memory and scientific cognition in AI research agents.

Diego F Cuadros, Abdoul-Aziz Maiga, Sid Thatham, Alvaro Ortiz, Margaret Powers-Fletcher, Ming Tang

Abstract read
In one paragraph

Article in Frontiers in big data, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Diego F CuadrosDigital Epidemiology Laboratory, Digital Futures, University of Cincinnati, Cincinnati, OH, United States.
Abdoul-Aziz MaigaNorwegian University of Science and Technology, Trondheim, Norway.
Sid ThathamUC Utilities, University of Cincinnati, Cincinnati, OH, United States.
Alvaro OrtizDepartment of Mathematical Sciences, University of Cincinnati, Cincinnati, OH, United States.
Margaret Powers-FletcherCollege of Arts and Sciences, University of Cincinnati, Cincinnati, OH, United States.
Ming TangSchool of Architecture and Interior Design, University of Cincinnati, Cincinnati, OH, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

AI research agents increasingly support ideation, literature search, coding, experimental execution, analysis, and manuscript drafting across the scientific workflow. This progress advances automated discovery, but workflow automation is not scientific cognition. Scientific reasoning is cumulative and path-dependent: it depends on what a researcher has written, read, learned from critique, absorbed through experience, and used as habitual standards for judging novelty, rigor, feasibility, and significance. We propose Mnemo as a framework for modeling scientific cognition in AI research agents. First, scientific cognition may require differentiated memory, organized into distinct spaces for authored work, external reference, critique, experience, and judgment. Second, provenance should be treated not as passive metadata but as memory routing, because source origin helps determine cognitive function in reasoning. Third, new ideas may be better modeled as controlled collisions across memory spaces, filtered by judgment, rejection, and epistemic calibration, than as generic recombination from model priors. Mnemo motivates a research agenda for AI in science centered on routing fidelity, critique use, judgment alignment, rejection quality, and epistemic calibration.

Indexed as

AI for scienceAI research agentscognitive architecturedifferentiated memorylarge language model agentsprovenancescientific cognitionscientific judgment

Identifiers

PMID42620683
PMCPMC13485561

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.