ArticleJPRAS open2026
Use of Matriderm in 2 cases of Dupuytren's contracture release.
Article in JPRAS open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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6 authors.
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Abstract
Dupuytren's contracture is a chronic fibroproliferative disorder of the hand characterized by progressive thickening and shortening of the palmar fascia, leading to flexion deformities of the fingers, particularly the ring and little fingers (1). The exact pathogenesis remains incompletely understood, however, both genetic and environmental factors play significant roles in disease development (2,3). This report highlights the use of Matriderm, a single-layer matrix consisting of collagen and elastin, possibly aiding postoperative outcomes of Dupuytren's Contracture. A 43-year-old female patient presented with Dupuytren's contracture of the fifth digit of the left hand. With a positive family history: her father exhibited the most severe form of the condition, possibly exacerbated by his work in the mechanical industry. Matriderm was used in surgeries in both cases, promoting wound healing and adhesiogenic regulation. These properties seemingly helped minimize postoperative scarring, improve joint mobility, and functional outcome.
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