Evidence map›Paper›PMID 42620425›Full record

ArticleFrontiers in psychiatry2026

Why dementia is often not diagnosed by subtype: care pathways and imaging access in the United Arab Emirates.

Syed Fahad Javaid, Fadwa Al Mugaddam, Zubaida Shebani, Syed Ali Bokhari

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Article in Frontiers in psychiatry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Syed Fahad JavaidDepartment of Psychiatry, College of Medicine and Health Sciences, United Arab Emirates University, Al Ain, United Arab Emirates.
Fadwa Al MugaddamDepartment of Psychiatry, College of Medicine and Health Sciences, United Arab Emirates University, Al Ain, United Arab Emirates.
Zubaida ShebaniDepartment of Behavioral Medicine, College of Medicine and Health Sciences, Sultan Qaboos University, Muscat, Oman.
Syed Ali BokhariAl Amal Psychiatric Hospital, Emirates Health Services, Dubai, United Arab Emirates.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Whether a person with dementia receives a specific subtype diagnosis rather than a nonspecific label is a marker of diagnostic completeness. Subtype shapes safe management, including psychotropic prescribing, behavioural and psychological symptom management, and eligibility for Alzheimer's disease therapies, yet nonspecific labels remain common where specialist assessment is unevenly accessed. We examined which patient, clinical, and service-pathway factors were associated with specific subtype assignment in a dementia cohort in the United Arab Emirates (UAE), and whether an exploratory model could help identify patients who might remain without a subtype. The outcome reflects the specificity of the recorded diagnosis, not adjudicated accuracy. Methods: We conducted a retrospective cohort study of patients with dementia seen at the Behavioural Sciences Institute, Al Ain Hospital from 1 January 2010 to 31 December 2019. The primary outcome was specific subtype assignment versus unspecified dementia. Factors examined were age, sex, nationality, brain imaging utilisation, comorbidity burden, symptom cluster, location of first assessment, and year. We fitted multivariable logistic regression with internal validation, sensitivity analyses, multiple imputation, scanned-subgroup analysis, and decision-curve analysis. Results: Of 825 patients, 786 entered the complete-case analytic sample; 336 (42.7%) had an unspecified diagnosis and 450 (57.3%) received a specific subtype label. Brain imaging showed the strongest adjusted association with specific subtype assignment (adjusted odds ratio = 4.00; 95% confidence interval = 2.84-5.63). Lower odds of specific assignment were associated with three or more comorbidities (0.40, 0.29-0.57), behavioural presentation (0.60, 0.39-0.94), emergency department route (0.29, 0.16-0.51), other route (0.31, 0.20-0.48), and neurology inpatient route (0.44, 0.22-0.90). Among scanned patients, multimorbidity and nonclinic routes remained associated with unspecified labelling. The prescan model showed positive net benefit across thresholds of 0.20-0.50. Conclusions: Diagnostic completeness was associated less with demographics than with imaging access, clinical complexity, and route of entry to care. Maintaining access to imaging within dementia pathways, and to timely specialist psychiatric assessment for acute and nonspecialist routes, may be associated with more complete subtype recording in the UAE and comparable Gulf systems. An exploratory prescan model identified patients at risk of remaining without a recorded subtype, though external validation is required before clinical use.

Indexed as

behavioural and psychological symptoms of dementiacare pathwaysdementiadiagnostic completenessmental health services researchneuroimagingold age psychiatryUnited Arab Emirates

Identifiers

PMID42620425
PMCPMC13485901

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