Evidence map›Paper›PMID 42620421›Full record

ReviewBrain & spine2026

Ventriculoperitoneal shunt versus transverse sinus stenting in idiopathic intracranial hypertension: A systematic review and meta-analysis.

Badr Hafiz, Alaa Turkistani, Waseem Alharthi, Tala Alsindi, Retaj Faisal Arif, Mohammed Binmahfoodh, Mohammed Aref

Abstract readReview
In one paragraph

Review in Brain & spine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Badr HafizDepartment of Neurosciences, King Faisal Specialist Hospital and Research Centre, Jeddah, Saudi Arabia.
Alaa TurkistaniDepartment of Neurosciences, King Faisal Specialist Hospital and Research Centre, Jeddah, Saudi Arabia.
Waseem AlharthiCollege of Medicine, Taif University, Taif, Saudi Arabia.
Tala AlsindiNeurosurgery Section, Department of Surgery, King Abdulaziz University Hospital, Jeddah, Saudi Arabia.
Retaj Faisal ArifDepartment of Surgery, Royal College of Surgeons, Dublin, Ireland.
Mohammed BinmahfoodhDepartment of Neurosciences, King Faisal Specialist Hospital and Research Centre, Jeddah, Saudi Arabia.
Mohammed ArefDepartment of Neurosciences, King Faisal Specialist Hospital and Research Centre, Jeddah, Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Idiopathic intracranial hypertension (IIH) is characterized by elevated intracranial pressure with risk of visual impairment. Ventriculoperitoneal shunting (VPS) and transverse sinus stenting (TSS) are commonly used surgical options, but comparative evidence remains limited. Methods: This systematic review and meta-analysis followed PRISMA guidelines and was registered in PROSPERO (CRD420251050247). PubMed, Web of Science, Cochrane CENTRAL, Embase, and Scopus were searched (2000-2025). Adult IIH patients treated with VPS or TSS were included. Random-effects meta-analysis was performed. Results: Seventeen studies were included. Intracranial pressure reduction was significant following TSS (SMD -4.58; 95% CI: -5.72 to -3.44; Conclusion: VPS and TSS provide comparable clinical outcomes in IIH. TSS demonstrated numerically lower revision rates, although without statistical significance. These findings should be interpreted cautiously because the available evidence is derived predominantly from non-randomized, indirect comparisons with substantial indication bias, and the treatment groups likely differed systematically at baseline. Prospective phenotype-guided comparative studies are needed to better define the optimal surgical strategy.

Indexed as

Cerebrospinal fluid shuntsEndovascular proceduresHeadache disordersIdiopathic intracranial hypertensionVentriculoperitoneal shunt

Identifiers

PMID42620421
PMCPMC13485500

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.