Evidence map›Paper›PMID 42620380›Full record

ArticleJPRAS open2026

Exploring perfusion limits in pedicled perforator propeller flaps via intraoperative indocyanine green angiography.

Adrian Sebald, Ingo Ludolph, Corinna Mundschau, Andreas Arkudas, Raymund E Horch

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Article in JPRAS open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Adrian SebaldDepartment of Plastic and Handsurgery and Laboratory for Tissue Engineering and Regenerative Medicine, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nuernberg FAU, Chair. Univ.-Prof. Dr. Prof.h.c. Dr.h.c. Raymund E Horch, Krankenhausstrasse 12, 91054 Erlangen, Germany.
Ingo LudolphDepartment of Plastic and Handsurgery and Laboratory for Tissue Engineering and Regenerative Medicine, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nuernberg FAU, Chair. Univ.-Prof. Dr. Prof.h.c. Dr.h.c. Raymund E Horch, Krankenhausstrasse 12, 91054 Erlangen, Germany.
Corinna MundschauDepartment of Plastic and Handsurgery and Laboratory for Tissue Engineering and Regenerative Medicine, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nuernberg FAU, Chair. Univ.-Prof. Dr. Prof.h.c. Dr.h.c. Raymund E Horch, Krankenhausstrasse 12, 91054 Erlangen, Germany.
Andreas ArkudasDepartment of Plastic and Handsurgery and Laboratory for Tissue Engineering and Regenerative Medicine, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nuernberg FAU, Chair. Univ.-Prof. Dr. Prof.h.c. Dr.h.c. Raymund E Horch, Krankenhausstrasse 12, 91054 Erlangen, Germany.
Raymund E HorchDepartment of Plastic and Handsurgery and Laboratory for Tissue Engineering and Regenerative Medicine, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nuernberg FAU, Chair. Univ.-Prof. Dr. Prof.h.c. Dr.h.c. Raymund E Horch, Krankenhausstrasse 12, 91054 Erlangen, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Pedicled perforator propeller flaps are widely used for soft-tissue reconstruction because they preserve donor-site function while providing reliable defect coverage. However, intraoperative assessment of flap perfusion remains challenging, particularly in longer flaps or after axial rotation. Indocyanine green (ICG) fluorescence angiography allows real-time visualization of tissue perfusion and may improve intraoperative decision-making. Methods: A retrospective single-center study was performed including 30 patients who underwent reconstruction with pedicled perforator propeller flaps between 2014 and 2022. Intraoperative ICG angiography was performed using the SPY-Elite system after flap elevation and after inset. A total of 48 angiographic sequences were analyzed using ImageJ software. Fluorescence intensity, perfusion distribution, and contour levels (20% and 30%) were evaluated across standardized 3-cm flap segments from the perforator origin to the distal flap edge. Results: All flaps survived, resulting in a flap survival rate of 100%. Postoperative complications occurred in 6 patients (20%), including 3 cases of minor wound-healing disorders and 3 cases of venous congestion requiring revision. Mean flap length was 15.8 cm. The average perfused area at the 20% fluorescence contour level represented 97.2% of the total flap surface. Perfusion decreased progressively with increasing distance from the perforator and declined significantly in flaps exceeding 15 cm in length ( Conclusions: Intraoperative ICG fluorescence angiography provides a reliable method for assessing perfusion in pedicled perforator propeller flaps. Perfusion mapping suggests that flap lengths under 10 cm and tissue areas within the 20%-30% fluorescence contour levels are associated with consistent viability. ICG angiography may therefore serve as a useful adjunct to optimize flap design and enhance surgical safety in reconstructive procedures.

Indexed as

Flap design optimizationIndocyanine green angiography (ICG-A)Intraoperative perfusion assessmentPedicled perforator propeller flap (PPF)

Identifiers

PMID42620380
PMCPMC13485620

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