Evidence map›Paper›PMID 42620260›Full record

ArticlebioRxiv : the preprint server for biology2026

CATSPERβ-δ Interaction Governs Hierarchical CatSper Holo-complex Assembly and is Essential for Male Fertility.

Jong-Nam Oh, Huafeng Wang, Tse-En Wang, Xiaofang Huang, Leonard K Kaczmarek, Jean-Ju Chung

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jong-Nam OhDepartment of Cellular and Molecular Physiology, Yale School of Medicine, New Haven, CT, USA.ORCID 0000-0001-9026-3725
Huafeng WangDepartment of Cellular and Molecular Physiology, Yale School of Medicine, New Haven, CT, USA.ORCID 0000-0002-7326-4379
Tse-En WangDepartment of Cellular and Molecular Physiology, Yale School of Medicine, New Haven, CT, USA.
Xiaofang HuangDepartment of Cellular and Molecular Physiology, Yale School of Medicine, New Haven, CT, USA.ORCID 0000-0003-1090-8349
Leonard K KaczmarekDepartment of Pharmacology, Yale School of Medicine, New Haven, CT 06510, USA.ORCID 0000-0001-5128-6326
Jean-Ju ChungDepartment of Cellular and Molecular Physiology, Yale School of Medicine, New Haven, CT, USA.ORCID 0000-0001-8018-1355

Funding

CatSper regulation of sperm physiology and fertilityR01HD096745 · NICHD · YALE UNIVERSITY · PI Jean-Ju Lucia Chung · 2019 to 2026
$3.4M
NICHD NIH HHS R01 HD096745
6 · The paper itself

Abstract

The sperm-specific CatSper channel is macromolecular Ca2+ channel complex essential for hyperactivated motility and male fertility. The pore-forming channel (CATSPER1-4) associates with a large extracellular domain-containing canopy (CATSPERβ-ε), a cytosolic Ca

Identifiers

PMID42620260
PMCPMC13484710

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.