Evidence map›Paper›PMID 42620256›Full record

ArticleFrontiers in endocrinology2026

Adverse cardio-metabolic risk profile and epicardial adiposity in patients with adrenal adenoma: a cross-sectional study.

Helena Niziolek, Ivica Just, Anna Tosin, Clemens Baumgartner, Oliver Koldyka, Konrad Körmöczi, Paul Fellinger, Hannes Beiglböck, Luise Bellach, Oliver Domenig and 12 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in endocrinology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Helena NiziolekDivision of Endocrinology and Metabolism, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria.
Ivica JustDivision of Endocrinology and Metabolism, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria.
Anna TosinDivision of Endocrinology and Metabolism, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria.
Clemens BaumgartnerDivision of Endocrinology and Metabolism, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria.
Oliver KoldykaDivision of Endocrinology and Metabolism, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria.
Konrad KörmöcziDivision of Endocrinology and Metabolism, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria.
Paul FellingerDivision of Endocrinology and Metabolism, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria.
Hannes BeiglböckDivision of Endocrinology and Metabolism, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria.
Luise BellachDivision of Endocrinology and Metabolism, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria.
Oliver DomenigAttoquant Diagnostics, Vienna, Austria.
Maximilian ZeydaDivision of Pediatric Pulmonology, Allergology and Endocrinology, Department of Pediatrics and Adolescent Medicine, Medical University of Vienna, Vienna, Austria.
Hansjörg HabischDivision of Medicinal Chemistry, Otto Loewi Research Center for Vascular Biology, Immunology and Inflammation, Medical University of Graz, Graz, Austria.
Tobias MadlDivision of Medicinal Chemistry, Otto Loewi Research Center for Vascular Biology, Immunology and Inflammation, Medical University of Graz, Graz, Austria.
Anton LugerDivision of Endocrinology and Metabolism, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria.
Greisa VilaDivision of Endocrinology and Metabolism, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria.
Siegfried TrattnigDepartment of Biomedical Imaging and Image Guided Therapy, Medical University of Vienna, Vienna, Austria.
Alexandra Kautzky-WillerDivision of Endocrinology and Metabolism, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria.
Thomas SchererDivision of Endocrinology and Metabolism, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria.
Michael LeutnerDivision of Endocrinology and Metabolism, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria.
Michael KrebsDivision of Endocrinology and Metabolism, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria.
Martin KrssakDivision of Endocrinology and Metabolism, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria.
Peter WolfDivision of Endocrinology and Metabolism, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Mild autonomous cortisol secretion (MACS) is associated with an increased cardiovascular mortality, but even patients with non-functioning adrenal adenoma (NFA) might be at risk for cardio-metabolic comorbidities compared to a control group with absence of an adrenal tumor (CON). Material and methods: Seventyfour individuals were included in cross-sectional analysis [MACS: n=25(84% females), age: 63(55-67)years, BMI:27.00(24.20-30.50)kg/m Results: The prevalence of hypertension (MACS:84% Conclusions: In this exploratory study, MACS was associated with epicardial adiposity and an adverse cardio-metabolic risk profile.

Indexed as

AdiposityAdrenal Gland NeoplasmsAdrenocortical AdenomaCardiovascular DiseasesAgedCross-Sectional StudiesEpicardial Adipose TissueFemaleHumansHypertensionMaleMiddle AgedRisk Factorsadrenal adenomacardiometabolic riskcross-sectional analysishepatic lipid accumulationmild autonomous cortisol secretion

Identifiers

PMID42620256
PMCPMC13485594

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.