Evidence map›Paper›PMID 42620120›Full record

ArticlebioRxiv : the preprint server for biology2026

MtvS1 and MtvS2 Interact with RNA Polymerase to Regulate the

Maj Brodmann, Christian F Baca, Joshua Chandanani, Elizabeth A Campbell, Luciano A Marraffini

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Maj BrodmannLaboratory of Bacteriology, The Rockefeller University, New York, NY 10065, USA.
Christian F BacaLaboratory of Bacteriology, The Rockefeller University, New York, NY 10065, USA.
Joshua ChandananiLaboratory of Molecular Biophysics, The Rockefeller University, New York, NY 10065, USA.
Elizabeth A CampbellLaboratory of Molecular Pathogenesis, The Rockefeller University, New York, NY 10065, USA.
Luciano A MarraffiniLaboratory of Bacteriology, The Rockefeller University, New York, NY 10065, USA.

Funding

Structural and functional studies of the mycobacterial transcription cycleR35GM151879 · NIGMS · ROCKEFELLER UNIVERSITY · PI ELIZABETH A CAMPBELL · 2024 to 2026
$1.4M
NIGMS NIH HHS R35 GM151879
6 · The paper itself

Abstract

Bacteria and archaea often harbor multiple CRISPR-Cas loci to defend against mobile genetic elements. Little is known, however, about whether and how different CRISPR-Cas systems are differentially regulated, in many instances due to the impossibility of studying CRISPR immunity in native hosts. Here we investigated the regulation of the endogenous type II-B and type V-A CRISPR-Cas systems present in the opportunistic human pathogen

Identifiers

PMID42620120
PMCPMC13484505

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.