Evidence map›Paper›PMID 42620039›Full record

ArticleArXiv2026

Unveiling neuronal microstructure in the human brain

Ante Zhu, Jerome J Maller, H Douglas Morris, Jeffrey P Guenette, Flavio Dell' Acqua, Chu-Yu Lee, Jeffrey McGovern, Stephan E Maier, Raymond Y Huang, Andrew L Alexander and 7 more

Abstract readPreprint
PubMed Full text at PMC
In one paragraph

Article in ArXiv, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Ante ZhuTechnology & Innovation Center, GE HealthCare, Niskayuna, NY, USA.
Jerome J MallerDepartment of Radiology, The University of Iowa, Iowa City, IO, USA.
H Douglas MorrisUniformed Services University, Bethesda, MD, USA.
Jeffrey P GuenetteDepartment of Radiology, Mass General Brigham, Harvard Medical School, Boston, MA, USA.
Flavio Dell' AcquaNeuroimaging and Biophysics Lab, Department of Neuroimaging, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.
Chu-Yu LeeDepartment of Radiology, The University of Iowa, Iowa City, IO, USA.
Jeffrey McGovernMRI Engineering, GE HealthCare, Waukesha, WI, USA.
Stephan E MaierDepartment of Radiology, Mass General Brigham, Harvard Medical School, Boston, MA, USA.
Raymond Y HuangDepartment of Radiology, Mass General Brigham, Harvard Medical School, Boston, MA, USA.
Andrew L AlexanderWaisman Center, University of Wisconsin-Madison, Madison, WI, USA.
Maureen N HoodUniformed Services University, Bethesda, MD, USA.
Desmond Teck Beng YeoTechnology & Innovation Center, GE HealthCare, Niskayuna, NY, USA.
Steven Cr WilliamsDepartment of Neuroimaging, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.
Carl-Fredrik WestinDepartment of Radiology, Mass General Brigham, Harvard Medical School, Boston, MA, USA.
Vincent B HoUniformed Services University, Bethesda, MD, USA.
Vincent A MagnottaDepartment of Radiology, The University of Iowa, Iowa City, IO, USA.
Hua LiMRI Engineering, GE HealthCare, Waukesha, WI, USA.

Funding

Enabling clinical tissue microstructure imaging as a diagnostic tool in wide-bore 3T MRIU01EB034313 · NIBIB · GENERAL ELECTRIC GLOBAL RESEARCH CTR · PI Oguz Akin, Thomas K Foo · 2023 to 2026
$4.1M
High Performance Gradient System for Advanced Neuroimaging ResearchS10OD030415 · OD · UNIVERSITY OF WISCONSIN-MADISON · PI ALEXANDER, ANDREW L · 2021 to 2021
$2.0M
NIBIB NIH HHS U01 EB034313NIH HHS S10 OD030415
6 · The paper itself

Abstract

Diffusion time-dependence, defined as variations in diffusivity and/or diffusional kurtosis with diffusion time, has emerged as a valuable non-invasive imaging marker for characterizing tissue microstructural features, such as cell size, density, packing disorder, and membrane permeability. In white matter, diffusion time-dependent changes between the short diffusion time and long diffusion time in radial diffusivity (RD), defined as the diffusivity perpendicular to fiber tracts, were demonstrated to correlate strongly with mean axon diameter in

Indexed as

axonal diameterhuman high-performance gradientneuronal microstructureoscillating gradient spin echoradial diffusivitytime-dependent diffusion

Identifiers

PMID42620039
PMCPMC13484421

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.