Evidence map›Paper›PMID 42619740›Full record

ArticlebioRxiv : the preprint server for biology2026

KIN-29 SIK regulates stress-induced sleep through mitochondrial redox signaling.

Pearson McIntire, Laura N Farrell, Suraiya Haroon, David M Raizen, Alexander M van der Linden

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Pearson McIntireDepartment of Biology, University of Nevada, Reno, Nevada, 89557.ORCID 0000-0003-2624-6001
Laura N FarrellDepartment of Neurology, Perelman School of Medicine, University of Pennsylvania.
Suraiya HaroonMitochondrial Medicine Frontier Program, Division of Genetics and Genomic Medicine, Department of Pediatrics, The Children's Hospital of Philadelphia, Philadelphia, PA.ORCID 0000-0001-5575-4609
David M RaizenDepartment of Neurology, Perelman School of Medicine, University of Pennsylvania.ORCID 0000-0001-5935-0476
Alexander M van der LindenDepartment of Biology, University of Nevada, Reno, Nevada, 89557.ORCID 0000-0002-4870-7684

Funding

Supplement for Google cloud build-outR24GM137786 · NIGMS · UNIV OF ARKANSAS FOR MED SCIS · PI Alan Tackett · 2020 to 2026
$15.4M
Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Ann E. Rougvie · 2012 to 2026
$7.5M
Virtual and Augmented Reality Interaction CoreP30GM145646 · NIGMS · UNIVERSITY OF NEVADA RENO · PI Jacqueline C Walsh-Snow · 2022 to 2026
$6.8M
Mechanism of Sleep Regulation by SIK3R01NS107969 · NINDS · UNIVERSITY OF PENNSYLVANIA · PI David Menassah Raizen, Alexander M Van der Linden · 2019 to 2026
$2.9M
ROS as a somnogenic signal in the metabolic regulation of sleepF31NS134153 · NINDS · UNIVERSITY OF NEVADA RENO · PI MCINTIRE, PEARSON · 2024 to 2025
$75k
NIGMS NIH HHS P30 GM145646NIGMS NIH HHS R24 GM137786NIH HHS P40 OD010440NINDS NIH HHS F31 NS134153NINDS NIH HHS R01 NS107969
6 · The paper itself

Abstract

The

Indexed as

C. elegansmetabolismReactive Oxygen SpeciesROSSIK3sleepSOD

Identifiers

PMID42619740
PMCPMC13483874

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.