Evidence map›Paper›PMID 42619221›Full record

ArticleLasers in surgery and medicine2026

Vaginal Laser Treatment for Genitourinary Syndrome of the Menopause: A Dose-Determining Study in Breast Cancer Survivors.

Sine Jacobsen, Marianne Glavind-Kristensen, Anders Bonde Jensen, Axel Forman, Vibe Munk Bertelsen, Pinar Bor

Abstract read
In one paragraph

Article in Lasers in surgery and medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sine JacobsenDepartment of Obstetrics and Gynaecology, Randers Regional Hospital, Randers NØ, Denmark.ORCID https://orcid.org/0000-0002-9500-5001
Marianne Glavind-KristensenDepartment of Obstetrics and Gynaecology, Aarhus University Hospital, Aarhus, Denmark.
Anders Bonde JensenDepartment of Clinical Medicine, Aarhus University, Aarhus N, Denmark.
Axel FormanDepartment of Obstetrics and Gynaecology, Aarhus University Hospital, Aarhus, Denmark.
Vibe Munk BertelsenDepartment of Obstetrics and Gynaecology, Randers Regional Hospital, Randers NØ, Denmark.ORCID https://orcid.org/0000-0003-3663-9431
Pinar BorDepartment of Clinical Medicine, Aarhus University, Aarhus N, Denmark.

Funding

The A.P. Moeller Foundation for the Advancement of Medical Science L-2023-00119The Danish Cancer Society R325-A18816The Danish Medical Association's Research Fund 2023-0090The Health Research Foundation of Central Denmark RegionThe Research Fund, Randers Regional Hospital, Denmark
6 · The paper itself

Abstract

objectivesBreast cancer survivors (BCSs) receiving endocrine therapy frequently develop genitourinary syndrome of menopause, characterized by vaginal dryness, pain, and urinary symptoms. Fractional CO

methodsThis single-center dose-determining study was conducted at Randers Regional Hospital, Denmark. Thirty BCSs on endocrine therapy with symptomatic genitourinary syndrome of menopause underwent five monthly sessions of fractional microablative CO

resultsTwenty-seven participants (90%) completed all five sessions. Vaginal dryness decreased significantly after three treatments, with a further incremental reduction by the fifth, representing the largest session-dependent change. FSFI scores increased significantly from baseline, with additional improvements across later sessions. SCS-W and ICIQ-FLUTSsex scores decreased steadily, while UDI-6 improved from baseline but remained stable across subsequent assessments. Treatments were well tolerated, with no serious adverse events.

conclusionsFractional CO

Indexed as

Breast NeoplasmsFemale Urogenital DiseasesLasers, GasMenopauseVaginal DiseasesAgedCancer SurvivorsFemaleHumansMiddle AgedSyndromeTreatment Outcomebreast cancer survivorsCO2 laserendocrine therapygenitourinary syndrome of menopausenon‐hormonal therapysexual functionvaginal atrophy

Identifiers

PMID42619221
PMCPMC13649092

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.