Evidence map›Paper›PMID 42618855›Full record

SynthesisJournal of general internal medicine2026

Improving Diagnostic Colonoscopy Completion After Positive Stool-Based Screening in Health-Disparity Populations: A Systematic Review and Meta-analysis.

Daniel A Gonzalez Mosquera, Maria B Mateo Chavez, Satya Sai Sri Bandi, Luis David Vilatuna-Andrango, Ivan Mateo Alzamora, Camila Wenczenovicz, Dante Souza, Shubhangi Bagewadi, Michael R Gionfriddo, Nehad Shabarek and 1 more

Abstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Journal of general internal medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Daniel A Gonzalez MosqueraDepartment of Internal Medicine, Lincoln Medical Center, Bronx, NY, USA.
Maria B Mateo ChavezKnowledge and Evaluation Research Unit, Rochester, MN, USA. mateochavez.maria@mayo.edu.ORCID http://orcid.org/0009-0008-1011-8949
Satya Sai Sri BandiKnowledge and Evaluation Research Unit, Rochester, MN, USA.
Luis David Vilatuna-AndrangoKnowledge and Evaluation Research Unit, Rochester, MN, USA.
Ivan Mateo AlzamoraKnowledge and Evaluation Research Unit, Rochester, MN, USA.
Camila WenczenoviczDepartment of Internal Medicine, TriHealth Inc, Cincinnati, OH, USA.
Dante SouzaDepartment of General Surgery, TriHealth Inc, Cincinnati, OH, USA.
Shubhangi BagewadiDepartment of Family Medicine, Louisiana State University Health Sciences Center Shreveport, Monroe, LA, USA.
Michael R GionfriddoGeisinger Medical Sciences, Scranton, PA, USA.
Nehad ShabarekDepartment of Internal Medicine, Lincoln Medical Center, Bronx, NY, USA.
Jean C FoxKnowledge and Evaluation Research Unit, Rochester, MN, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDelays in diagnostic colonoscopy after abnormal stool-based colorectal cancer screening are common in health-disparity populations and are associated with more advanced-stage disease at diagnosis. We evaluated the effectiveness of interventions designed to increase completion of diagnostic colonoscopy after abnormal fecal immunochemical test (FIT) or fecal occult blood test (FOBT) results in these populations.

methodsWe searched six databases from inception through September 23, 2024 (updated June 4, 2025), for randomized trials, nonrandomized controlled studies, and controlled pre-post studies of interventions to improve colonoscopy completion after abnormal FIT or FOBT in health-disparity populations, as defined by the U.S. Department of Health and Human Services. Risk of bias was assessed with RoB 2 and ROBINS-I and certainty with GRADE. Studies were pooled within intervention types (PROSPERO CRD42024591109).

resultsTen studies met inclusion criteria: patient navigation (8), a registry-based quality-improvement collaborative (1), and low-touch result notification (1). In the registered primary analysis-navigation, with completion over each study's own window-navigation increased completion versus usual care (risk ratio [RR], 1.27; 95% CI, 1.10-1.46; moderate certainty). The effect was stable when all interventions were pooled as registered (RR, 1.28; 95% CI, 1.12-1.46) and across analytic choices, and was consistent in post hoc analyses at 6 months (RR, 1.29; 95% CI, 0.97-1.71) and 12 months (RR, 1.34; 95% CI, 1.20-1.49; I DISCUSSION: Patient navigation improves timely diagnostic colonoscopy completion after abnormal stool-based screening in health-disparity populations (moderate certainty); other strategies increased completion but rest on single studies. Limitations include intervention heterogeneity, varying follow-up intervals, and few studies per intervention type. Standardized time-based follow-up benchmarks and expanded navigation may advance equity. This study received no external funding.

Indexed as

colonoscopycolorectal neoplasmsmass screeningmeta-analysissystematic review

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.