Evidence map›Paper›PMID 42618823›Full record

ArticleSurgical endoscopy2026

Prognostic nutritional index (PNI) is a predictor of adverse outcomes following open ventral hernia repair.

Andrew J Bedard, Brandon Dyer, Katherine Quesada Tibbetts, Dustin Rendell, Michael Albrink, Adham Saad, Joseph Adam Sujka, Salvatore Docimo, Christopher Garnet Ducoin, Monica Polcz

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Article in Surgical endoscopy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Andrew J BedardUSF Health Morsani College of Medicine, University of South Florida, Tampa, FL, USA.
Brandon DyerUSF Health Morsani College of Medicine, University of South Florida, Tampa, FL, USA.
Katherine Quesada TibbettsUSF Health Morsani College of Medicine, University of South Florida, Tampa, FL, USA.
Dustin RendellUSF Health Morsani College of Medicine, University of South Florida, Tampa, FL, USA.
Michael AlbrinkDepartment of Surgery, Morsani College of Medicine, University of South Florida, Tampa, FL, USA.
Adham SaadDepartment of Surgery, Morsani College of Medicine, University of South Florida, Tampa, FL, USA.
Joseph Adam SujkaDepartment of Surgery, Morsani College of Medicine, University of South Florida, Tampa, FL, USA.
Salvatore DocimoDepartment of Surgery, Morsani College of Medicine, University of South Florida, Tampa, FL, USA.
Christopher Garnet DucoinDepartment of Surgery, Morsani College of Medicine, University of South Florida, Tampa, FL, USA.
Monica PolczDepartment of Surgery, Morsani College of Medicine, University of South Florida, Tampa, FL, USA. monicapolcz@usf.edu.ORCID http://orcid.org/0000-0001-8744-5982

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionOptimization of modifiable risk factors prior to elective ventral hernia repair (VHR) improves outcomes. There is no well-established correlation between nutritional status and outcomes after VHR. Prognostic nutritional index (PNI) is a measure of immune and nutritional status, incorporating albumin and total lymphocyte count. We aim to evaluate the association between PNI and clinical outcomes after open VHR.

methodsWe retrospectively reviewed adult patients who underwent open elective VHR (> 3 cm) between 2023 and 2025 with recent (< 1 month preop) albumin and lymphocyte count, categorized as low PNI (< 45) or normal PNI (≥ 45). Statistical analyses included standard univariate and multivariate logistic regression.

results125 patients were included; 42 (33.6%) with low and 83 (66.4%) with normal PNI. 62.4% were male, 75.2% ASA III-IV, 32.8% diabetic, with 32% recurrent hernia on presentation and average defect size of 85.53 ± 98.82cm

conclusionPNI is an independent predictor of surgical site infection after open VHR, and results in longer LOS and higher utilization of rehabilitation services post-discharge. This data may help inform preoperative discussions and risk-stratification. Further studies are warranted to determine whether immunomodulating supplements before elective VHR may improve these measures in patients with low PNI.

Indexed as

Hernia, ventralNutritional assessmentNutritional status

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.