Evidence map›Paper›PMID 42618822›Full record

ArticleSurgical endoscopy2026

Development and validation of 3D-printed anatomically accurate liver model for endoscopic ultrasound-based endo-hepatology training (with video).

Abdulrahman Qatomah, Leander Heisterberg, Ravi Teja Pasam, Wafa Qatomah, Daryl Ramai, Christopher C Thompson, Marvin Ryou

Abstract readVideo-Audio MediaValidation Study
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Article in Surgical endoscopy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Abdulrahman Qatomah *Division of Gastroenterology, Hepatology and Endoscopy, Brigham and Women's Hospital, Harvard Medical School, 75 Francis St, Boston, MA, 02115, USA.ORCID http://orcid.org/0000-0001-9528-6301
Leander Heisterberg *Division of Gastroenterology, Hepatology and Endoscopy, Brigham and Women's Hospital, Harvard Medical School, 75 Francis St, Boston, MA, 02115, USA.
Ravi Teja PasamDivision of Gastroenterology, Hepatology and Endoscopy, Brigham and Women's Hospital, Harvard Medical School, 75 Francis St, Boston, MA, 02115, USA.
Wafa QatomahDepartment of Medical Imaging, Ministry of the National Guard-Health Affairs, Riyadh, Saudi Arabia.
Daryl RamaiDivision of Gastroenterology, University of Utah, Salt Lake City, UT, USA.
Christopher C ThompsonDivision of Gastroenterology, Hepatology and Endoscopy, Brigham and Women's Hospital, Harvard Medical School, 75 Francis St, Boston, MA, 02115, USA.
Marvin RyouDivision of Gastroenterology, Hepatology and Endoscopy, Brigham and Women's Hospital, Harvard Medical School, 75 Francis St, Boston, MA, 02115, USA. mryou@bwh.harvard.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEx vivo endoscopic ultrasound (EUS) training relies on animal tissue, which is anatomically variable, perishable, and requires dedicated endoscopes. As EUS-based liver assessment (EUS-LA)-including parenchymal imaging, shear-wave elastography (SWE), attenuation imaging, and EUS-guided liver biopsy (EUS-LB)-expands, an anatomically accurate, tissue-free training platform could be a valuable educational tool. We developed a synthetic training tool that integrated a gelatin liver and silicone foregut and assessed its validity.

methodsCT data from a healthy female were extracted to three-dimensionally print a liver replica. The replica was used to create a negative mold to cast a gelatin matrix around color-coded vasculature, then integrated with silicone esophagus/stomach/duodenum model to recreate normal foregut/liver anatomy. Sixteen endoscopists (12 experts from five centers in two countries; 4 novices) performed standardized EUS-LA across four tasks. Content validity (12 experts) was summarized with a content-validity index (CVI); inter-rater agreement used Gwet's AC1 with 95% confidence intervals (CI); face validity and global satisfaction were assessed in all 16.

resultsComposite CVI was 0.85 (AC1 0.68, 95% CI 0.54-0.83; p < 0.0001). CVI realism was 0.87, with perfect endorsement for liver parenchyma (1.00; AC1 0.90) and high endorsement for quantitative imaging (0.95; AC1 0.88); vascular realism was lower (0.73), with expert agreement no better than chance (AC1 0.41; p = 0.17). CVI relevance was 0.90 and representativeness 0.77. The complete workflow, including the EUS-LB maneuver, vessel avoidance, and SWE/attenuation acquisition, was completed by 100% of evaluable participants. All endorsed use before ex vivo training, and 93.8% would recommend the model; global satisfaction was 4.25 (IQR 4-5).

conclusionsThe anatomically accurate, synthetic training model showed strong content and face validity and supported the complete diagnostic endo-hepatology workflow in a reproducible manner. Vascular realism is the principal target for refinement.

Indexed as

EndosonographyGastroenterologyLiverModels, AnatomicPrinting, Three-DimensionalFemaleHumansContent validityEndo-hepatologyEndoscopic ultrasoundGelatinPhantomSimulation training

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.