Evidence map›Paper›PMID 42618781›Full record

ArticleNature2026

An Icelandic pangenome reference.

Guillaume Holley, Hannes P Eggertsson, Snaedis Kristmundsdottir, Doruk Beyter, Astros Th Skuladottir, Kristjan H S Moore, Pall I Olason, Arnaldur Gylfason, Olafur T Magnusson, Asmundur Oddsson and 7 more

Abstract read
PubMed Publisher
In one paragraph

Article in Nature, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Guillaume Holley *deCODE genetics/Amgen, Reykjavik, Iceland. gholley@amgen.com.ORCID http://orcid.org/0009-0008-2211-9957
Hannes P Eggertsson *deCODE genetics/Amgen, Reykjavik, Iceland. heggerts@amgen.com.ORCID http://orcid.org/0000-0002-1674-9978
Snaedis KristmundsdottirdeCODE genetics/Amgen, Reykjavik, Iceland.ORCID http://orcid.org/0000-0001-8981-0883
Doruk BeyterdeCODE genetics/Amgen, Reykjavik, Iceland.
Astros Th SkuladottirdeCODE genetics/Amgen, Reykjavik, Iceland.ORCID http://orcid.org/0000-0002-5048-0933
Kristjan H S MooredeCODE genetics/Amgen, Reykjavik, Iceland.ORCID http://orcid.org/0000-0002-9579-4362
Pall I OlasondeCODE genetics/Amgen, Reykjavik, Iceland.
Arnaldur GylfasondeCODE genetics/Amgen, Reykjavik, Iceland.ORCID http://orcid.org/0000-0001-5912-4962
Olafur T MagnussondeCODE genetics/Amgen, Reykjavik, Iceland.
Asmundur OddssondeCODE genetics/Amgen, Reykjavik, Iceland.ORCID http://orcid.org/0000-0002-4606-5163
Hreinn StefanssondeCODE genetics/Amgen, Reykjavik, Iceland.ORCID http://orcid.org/0000-0002-9331-6666
Agnar HelgasondeCODE genetics/Amgen, Reykjavik, Iceland.
Gisli MassondeCODE genetics/Amgen, Reykjavik, Iceland.
Patrick SulemdeCODE genetics/Amgen, Reykjavik, Iceland.ORCID http://orcid.org/0000-0001-7123-6123
Daniel F GudbjartssondeCODE genetics/Amgen, Reykjavik, Iceland.ORCID http://orcid.org/0000-0002-5222-9857
Kari StefanssondeCODE genetics/Amgen, Reykjavik, Iceland.
Bjarni V HalldorssondeCODE genetics/Amgen, Reykjavik, Iceland.ORCID http://orcid.org/0000-0003-0756-0767

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Reference bias is an issue that affects most genomic studies analysing short reads mapped to a reference genome

Identifiers

PMID42618781

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.