Evidence map›Paper›PMID 42618628›Full record

ArticleHypertension research : official journal of the Japanese Society of Hypertension2026

Family history of hypertension may have a stronger association with the incidence of hypertension than previously estimated: the SBS study.

Yasuharu Tabara, Yoko Sato, Sayaka Nagao-Sato, Shin Koga

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Article in Hypertension research : official journal of the Japanese Society of Hypertension, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Yasuharu TabaraGraduate School of Public Health, Shizuoka Graduate University of Public Health, Shizuoka, Japan. tabara@s-sph.ac.jp.
Yoko SatoGraduate School of Public Health, Shizuoka Graduate University of Public Health, Shizuoka, Japan.
Sayaka Nagao-SatoGraduate School of Public Health, Shizuoka Graduate University of Public Health, Shizuoka, Japan.
Shin KogaPublic Interest Incorporated Foundation, SBS Shizuoka Health Promotion Center, Shizuoka, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A family history (FH) of hypertension is associated with an increased risk of new-onset hypertension. However, the risk of FH estimated in normotensives using conventional methods may have been somewhat underestimated by excluding early-onset cases, who are highly likely to have FH of hypertension. This large-scale longitudinal study on a middle-aged population (mean age: 46.8 years) revealed that the hazard ratio of FH of hypertension for the development of hypertension was higher when calculated for the entire study population (N = 34,792), including hypertensives at baseline by treating them as left-censored cases, using an interval-censored Cox proportional hazards model (1.73, 95% confidence interval: 1.67-1.79, P < 0.001) than that calculated in normotensives (n = 28,271) using a conventional Cox model (1.35, 95% confidence interval: 1.28-1.44, P < 0.001). The effect of changes in the possible confounders during the follow-up period was negligible. Thus, the risk of FH of hypertension for the development of hypertension may be higher than previously reported.

Indexed as

HypertensionAdultFemaleHumansIncidenceJapanLongitudinal StudiesMaleMiddle AgedProportional Hazards ModelsRisk FactorsFamily historyGeneral populationImplemental hypertensionInterval-censored Cox model

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.