Evidence map›Paper›PMID 42618602›Full record

ArticleMolecular psychiatry2026

The protective role of memory suppression in psychological resilience among young adults with childhood trauma.

Xiangwen Chang, Zhengyu Yang, Shiqiu Meng, Zhen Liu, Jiahui Deng, Peng Li, Xiao Lin, Le Shi, Sanwang Wang, Tingting Li and 4 more

Abstract read
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In one paragraph

Article in Molecular psychiatry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Xiangwen Chang *National Institute on Drug Dependence and Beijing Key Laboratory of Innovative Intervention Techniques and Translational Research for Mental Disorders Rehabilitation, Peking University, Beijing, 100191, China.
Zhengyu Yang *Institute of Science and Technology for Brain-Inspired Intelligence, Fudan University, Shanghai, 200433, China.
Shiqiu Meng *National Institute on Drug Dependence and Beijing Key Laboratory of Innovative Intervention Techniques and Translational Research for Mental Disorders Rehabilitation, Peking University, Beijing, 100191, China.
Zhen LiuNational Institute on Drug Dependence and Beijing Key Laboratory of Innovative Intervention Techniques and Translational Research for Mental Disorders Rehabilitation, Peking University, Beijing, 100191, China.
Jiahui DengPeking University Sixth Hospital, Peking University Institute of Mental Health, NHC Key Laboratory of Mental Health (Peking University), National Clinical Research Center for Mental Disorders (Peking University Sixth Hospital), Beijing, 100191, China.ORCID http://orcid.org/0000-0002-2025-0336
Peng LiPeking University Sixth Hospital, Peking University Institute of Mental Health, NHC Key Laboratory of Mental Health (Peking University), National Clinical Research Center for Mental Disorders (Peking University Sixth Hospital), Beijing, 100191, China.
Xiao LinPeking University Sixth Hospital, Peking University Institute of Mental Health, NHC Key Laboratory of Mental Health (Peking University), National Clinical Research Center for Mental Disorders (Peking University Sixth Hospital), Beijing, 100191, China.
Le ShiPeking University Sixth Hospital, Peking University Institute of Mental Health, NHC Key Laboratory of Mental Health (Peking University), National Clinical Research Center for Mental Disorders (Peking University Sixth Hospital), Beijing, 100191, China.ORCID http://orcid.org/0000-0003-4750-3492
Sanwang WangPeking University Sixth Hospital, Peking University Institute of Mental Health, NHC Key Laboratory of Mental Health (Peking University), National Clinical Research Center for Mental Disorders (Peking University Sixth Hospital), Beijing, 100191, China.
Tingting LiPeking University Sixth Hospital, Peking University Institute of Mental Health, NHC Key Laboratory of Mental Health (Peking University), National Clinical Research Center for Mental Disorders (Peking University Sixth Hospital), Beijing, 100191, China.
Lin LuNational Institute on Drug Dependence and Beijing Key Laboratory of Innovative Intervention Techniques and Translational Research for Mental Disorders Rehabilitation, Peking University, Beijing, 100191, China.ORCID http://orcid.org/0000-0003-0742-9072
Tianye JiaNational Institute on Drug Dependence and Beijing Key Laboratory of Innovative Intervention Techniques and Translational Research for Mental Disorders Rehabilitation, Peking University, Beijing, 100191, China. tianyejia@bjmu.edu.cn.ORCID http://orcid.org/0000-0001-5399-2953
Yan SunNational Institute on Drug Dependence and Beijing Key Laboratory of Innovative Intervention Techniques and Translational Research for Mental Disorders Rehabilitation, Peking University, Beijing, 100191, China. sunyan@bjmu.edu.cn.ORCID http://orcid.org/0000-0002-0443-6309
Jie ShiNational Institute on Drug Dependence and Beijing Key Laboratory of Innovative Intervention Techniques and Translational Research for Mental Disorders Rehabilitation, Peking University, Beijing, 100191, China. shijie@bjmu.edu.cn.ORCID http://orcid.org/0000-0001-6567-8160

Funding

National Natural Science Foundation of China (National Science Foundation of China) 82130040National Natural Science Foundation of China (National Science Foundation of China) 82288101
6 · The paper itself

Abstract

The mechanisms underlying psychological resilience following childhood trauma remain unclear. This study investigated whether memory suppression-the ability to inhibit unwanted memories voluntarily-serves as a key mechanism promoting resilience, and examined its neural correlates. An online survey of 2914 students assessed childhood trauma, resilience, and memory suppression ability, revealing that suppression ability significantly mediated the trauma-resilience relationship. Subsequently, 91 participants (grouped by trauma exposure and resilience levels) underwent fMRI during a Think/No-Think task. Behaviorally, high-resilience individuals exhibited superior memory suppression. Neuroimaging identified the left intraparietal sulcus (IPS) as a critical neural substrate, showing enhanced suppression-related activity in high-resilience individuals and mediating the association between suppression performance and resilience. Additionally, the left IPS displayed increased functional connectivity with cognitive control regions and decreased connectivity with memory-related regions during suppression, with no significant differences between groups. These results establish memory suppression as a central component of resilience and highlight the left IPS as a key neural adaptor, suggesting its potential as a target for clinical intervention.

Identifiers

PMID42618602

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.