ArticleInternational journal of obesity (2005)2026
Self-medication with GLP-1 receptor agonists among Brazilian Adults: findings from a web-based survey.
Article in International journal of obesity (2005), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundThe popularity of GLP-1 receptor agonists (GLP-1 RAs) for weight loss has increased significantly in recent years, raising concerns about self-medication with these medications.
objectiveTo assess the proportion and identify factors associated with GLP-1 RA use without medical prescription among GLP-1 RA users in Brazil.
methodsThis cross-sectional study was conducted through a self-administered online questionnaire including adults aged 18 years or older residing in Brazil who reported current or past use of GLP-1 RAs for weight loss. We reported the proportion of self-medication and explored associated factors using Poisson regression with robust variance, adjusting for potential confounders.
resultsA total of 860 participants were included (mean age: 39.46 ± 10.61 years; 82.0% female; 47.1% with obesity). The proportion of self-medication with GLP-1 RA was 23.8% (95% CI: 21.1-26.8%). Predictors of self-medication included not having obesity (PR = 1.45; 95% CI: 1.13-1.89), not attending physical training centers (PR = 1.55; 95% CI: 1.23-1.96), and working in healthcare-related professions (PR = 1.45; 95% CI: 1.14-1.84). Conversely, being married (PR = 0.73; 95% CI: 0.57-0.94), having diabetes (PR = 0.35; 95% CI: 0.18-0.70), or having eating disorders (PR = 0.72; 95% CI, 0.34-0.97) were associated with lower self-medication rates.
conclusionAlmost one in four users reported using GLP-1 RAs without medical prescription. This practice was more frequent among individuals without obesity, those not attending physical training centers, and healthcare professionals.
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Registered trials
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