Evidence map›Paper›PMID 42618554›Full record

ReviewBiological chemistry2026

Structural basis for the procoagulant activity of

Pablo Fuentes-Prior, Ashoka A Maddur, Peter Panizzi, David Gailani, Ingrid M Verhamme

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Biological chemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Pablo Fuentes-PriorDepartment of Biochemistry and Molecular Biomedicine, Faculty of Biology, Institute of Biomedicine of the University of Barcelona (IBUB), University of Barcelona (UB), E-08028, Barcelona, Spain.ORCID https://orcid.org/0000-0002-6618-3204
Ashoka A MaddurFUJIFILM Biotechnologies, College Station, TX, 77845, USA.
Peter PanizziDepartment of Drug Discovery and Development, Harrison College of Pharmacy, Auburn University, Auburn, AL, 36849-5506, USA.ORCID https://orcid.org/0000-0003-0141-8807
David GailaniDepartment of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, TN, 37232, USA.
Ingrid M VerhammeDepartment of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, TN, 37232, USA.

Funding

Roles of fibrin(ogen) in conformational activation of hemostatic proteinase precursorsR01HL158918 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI GAILANI, DAVID, VERHAMME, INGRID M · 2022 to 2025
$1.9M
Mechanism of Staphylocoagulase-activated Blood ClottingR01HL071544 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI BOCK, PAUL E, VERHAMME, INGRID M · 2003 to 2016
$1.8M
NHLBI NIH HHS R01 HL071544NHLBI NIH HHS R01 HL158918
6 · The paper itself

Abstract

Staphylocoagulase (SC), a crucial virulence protein secreted by several strains of the major pathogen

Indexed as

coagulationcofactor-assisted activationfibrinogenmolecular modelingStaphylococcus aureustrypsin-like serine proteinases

Identifiers

PMID42618554
PMCPMC13605537

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.