Evidence map›Paper›PMID 42617603›Full record

ArticleCurrent biology : CB2026

Voice perception reflects graded sensitivity to acoustic cues along the auditory hierarchy.

Jasmine L Hect, Kyle M Rupp, Avniel Singh Ghuman, Lori L Holt, Taylor J Abel

Abstract read
In one paragraph

Article in Current biology : CB, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jasmine L HectDepartment of Neurological Surgery, University of Pittsburgh, Pittsburgh, PA 15213, USA.
Kyle M RuppDepartment of Neurological Surgery, University of Pittsburgh, Pittsburgh, PA 15213, USA.
Avniel Singh GhumanDepartment of Neurological Surgery, University of Pittsburgh, Pittsburgh, PA 15213, USA.
Lori L HoltDepartment of Psychology, University of Texas, Austin, TX 78712, USA.
Taylor J AbelDepartment of Neurological Surgery, University of Pittsburgh, Pittsburgh, PA 15213, USA; Department of Bioengineering, University of Pittsburgh, Pittsburgh, PA 15213, USA; 4401 Penn Ave., Faculty Pavilion, 4th Floor, Office 4126, Pittsburgh, PA 15224, USA. Electronic address: abeltj@upmc.edu.

Funding

TRAINING PROGRAM FOR MD/PHD STUDENTST32GM008208 · NIGMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI STEINMAN, RICHARD A · 1987 to 2021
$15.4M
Supplement to cortical contributions to frequency-following response generation and modulationR01DC013315 · NIDCD · UNIVERSITY OF TEXAS AT AUSTIN · PI ABEL, TAYLOR JOHN, CHANDRASEKARAN, BHARATH · 2014 to 2025
$5.5M
Active Social Vision: How the Brain Processes Visual Information During Natural Social PerceptionR01MH132225 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI AVNIEL S GHUMAN, Louis-Philippe Morency · 2023 to 2026
$2.8M
Flexible representation of speech in the supratemporal plane.R21DC019217 · NIDCD · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI ABEL, TAYLOR JOHN, HOLT, LORI L · 2021 to 2022
$524k
Intracranial Electrophysiology & Anatomical Connectivity of Voice-Selective Auditory CortexF30DC021342 · NIDCD · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Jasmine Leah Hect · 2023 to 2026
$208k
NIDCD NIH HHS F30 DC021342NIDCD NIH HHS R01 DC013315NIDCD NIH HHS R21 DC019217NIGMS NIH HHS T32 GM008208NIMH NIH HHS R01 MH132225
6 · The paper itself

Abstract

Humans readily recognize voices in noisy, challenging environments, yet how the brain does this remains poorly understood. A key question is whether the brain is tuned to detect "voice-like" qualities present in sounds. To test this, we asked whether voice perception relies on sensitivity to acoustic patterns shared by human vocalizations. We developed a computational framework that identified the acoustic features most characteristic of human voices and examined how these features predict listener judgments of "voice-likeness" in both natural sounds and synthetic stimuli we designed to vary systematically in acoustic structure. We then recorded neural activity from implanted electrodes in the auditory brain regions of patients undergoing evaluation for epilepsy, asking whether these same acoustic patterns predict neural responses. Across the auditory cortex, neural activity aligned with this continuous scale of voice-likeness, and the strength of this alignment increased along the hierarchy from early to higher auditory areas but not in frontal auditory areas. These findings reveal that auditory association cortex implements a coding framework characterized by graded sensitivity to vocal acoustic patterns. This organization emerges progressively across auditory processing stages, suggesting that voice recognition reflects a fundamental principle: the brain uses continuous, graded representations to interpret the acoustic world and guide perception.

Indexed as

Auditory CortexAuditory PerceptionCuesVoiceVoice RecognitionAcoustic StimulationAdultFemaleHumansMaleauditory cortexauditory ventral streamcategorical perceptionelectrophysiologyiEEGintracranial EEGpsychoacousticssound texturespeech perceptionsuperior temporal gyrusvoice perception

Identifiers

PMID42617603
PMCPMC13595310

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.