Evidence map›Paper›PMID 42617113›Full record

ArticleWomen's health (London, England)

The monthly spectrum: Premenstrual symptoms across ADHD and autism.

Annabeth P Groenman, Lotte E Welling, Sara Pieters

Abstract read
In one paragraph

Article in Women's health (London, England). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Annabeth P GroenmanDepartment of Child and Adolescent Psychiatry Groningen, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.ORCID 0000-0002-8394-6605
Lotte E WellingResearch Institute of Child Development and Education, University of Amsterdam, Amsterdam, the Netherlands.
Sara PietersBehavioural Science Institute, Radboud University, Nijmegen, The Netherlands.ORCID 0009-0008-5914-4048

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BackgroundWomen with ADHD and autism experience elevated rates of premenstrual problems, yet no direct comparisons between these conditions exist in adults.ObjectivesThis study examined premenstrual dysphoric disorder (PMDD) prevalence, symptoms, and impairment across ADHD, autism, and neurotypical women.DesignCross-sectional data from 199 women aged 20-40 without hormonal contraceptive use were analyzed across two samples.MethodsParticipants included 89 with ADHD, 39 with autism, and 71 controls. Premenstrual symptoms were assessed using the Premenstrual Symptoms Screening Tool (PSST), alongside measures of ADHD characteristics, autism traits, and sensory hypersensitivity.ResultsBoth ADHD and autistic women showed significantly elevated provisional PMDD rates according to the PSST screening instrument compared to controls, with no significant difference between neurodivergent groups. Dimensional analyses revealed positive associations between premenstrual symptoms and neurodiverse traits, particularly inattention, hyperactivity-impulsivity, and social skills difficulties. The impact of premenstrual problems was similarly associated with these traits across diagnostic groups. Contrary to hypotheses, sensory hypersensitivity was not independently associated with premenstrual symptoms after controlling for ADHD and autism characteristics.ConclusionsPremenstrual problems constitute a significant burden for both ADHD and autistic women, with dimensional associations suggesting that individuals with more severe neurodivergent traits face heightened risk. Yet our findings also demonstrate that prevalence estimates are only as reliable as the recruitment strategies behind them. Advancing this field requires both greater clinical attention to menstrual cycle-related difficulties in neurodivergent populations and recruitment strategies that yield dependable estimates.

Indexed as

Attention Deficit Disorder with HyperactivityAutistic DisorderPremenstrual Dysphoric DisorderPremenstrual SyndromeAdultCross-Sectional StudiesFemaleHumansPrevalenceYoung AdultADHDautismneurodiversitypremenstrual complaints

Identifiers

PMID42617113
PMCPMC13662566

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.