Evidence map›Paper›PMID 42616868›Full record

ArticleScience advances2026

H3.3 chaperone Hira primes the effector program and function of regulatory T cells.

Xiangxiang Cao, Mengjie Lv, Zhihan Lv, Shuting Zheng, Xinyi Tan, Jiyu Ding, Wei Liang, Guohong Li, Xuyu Zhou, Mingzhao Zhu

Abstract read
In one paragraph

Article in Science advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Xiangxiang CaoKey Laboratory of Epigenetic Regulation and Intervention, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China.ORCID 0009-0009-9475-6450
Mengjie LvCAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China.ORCID 0009-0009-8915-3778
Zhihan LvKey Laboratory of Epigenetic Regulation and Intervention, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China.ORCID 0009-0005-6626-3596
Shuting ZhengCAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China.ORCID 0009-0004-3037-7252
Xinyi TanKey Laboratory of Epigenetic Regulation and Intervention, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China.ORCID 0009-0003-5146-2934
Jiyu DingCAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China.ORCID 0009-0004-3363-8411
Wei LiangCAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China.ORCID 0009-0008-1576-8086
Guohong LiKey Laboratory of Epigenetic Regulation and Intervention, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China.ORCID 0000-0003-2137-0783
Xuyu ZhouCAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China.ORCID 0000-0002-6626-0898
Mingzhao ZhuCAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China.ORCID 0000-0003-2001-2669

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Foxp3

Indexed as

Histone ChaperonesHistonesT-Lymphocytes, RegulatoryAnimalsBasic-Leucine Zipper Transcription FactorsCell DifferentiationChromatinEpigenesis, GeneticForkhead Transcription FactorsMiceMice, KnockoutBasic-Leucine Zipper Transcription FactorsBatf protein, mouseChromatinForkhead Transcription FactorsHistone ChaperonesHistones

Identifiers

PMID42616868
PMCPMC13488888

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.