Evidence map›Paper›PMID 42616867›Full record

ArticleScience advances2026

Programmable photonic neural engine with all-optical nonlinear activation and 40,000 connections.

Hao Sun, Xinyi Zhu, José Azaña

Abstract read
In one paragraph

Article in Science advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Hao SunInstitut National de la Recherche Scientifique, Centre Énergie Matériaux Telecommunications (INRS-EMT), Montréal, QC H5A-1K6, Canada.ORCID 0009-0008-6083-4126
Xinyi ZhuInstitut National de la Recherche Scientifique, Centre Énergie Matériaux Telecommunications (INRS-EMT), Montréal, QC H5A-1K6, Canada.
José AzañaInstitut National de la Recherche Scientifique, Centre Énergie Matériaux Telecommunications (INRS-EMT), Montréal, QC H5A-1K6, Canada.ORCID 0000-0003-0080-7181

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The rapid advancement of artificial neural networks (ANNs) demands computational platforms with higher speed, energy efficiency, and scalability. Optical computing offers an appealing solution owing to the high-speed processing, inherent parallelism, and low energy consumption. However, existing optical neural network architectures face fundamental trade-offs between scalability, reconfigurability, and processing latency, constrained by the need to rely on electronic nonlinearities or fixed optical interconnections. Here, we report an end-to-end photonic neuromorphic engine that integrates all-optical nonlinearity into a loop-based, time-multiplexed photonic architecture. This approach enables all optical neurons to share common hardware, supporting enhanced connectivity and full reconfigurability with reduced latency. Implementations of four distinct network topologies, with a maximum of 40,000 optical connections for the single-layer perceptron, achieve digital-level inference accuracy and computational latency over two orders of magnitude shorter than state-of-the-art electronic processors, potentially paving the way for scalable, reconfigurable, and ultrafast optical artificial intelligence systems.

Identifiers

PMID42616867
PMCPMC13488885

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.