ArticleAnnals of biomedical engineering2026
Shear-Wave Anisotropy of the Vastus Lateralis During Low-Level Isometric Contraction Measured with Ultrasound Time-Harmonic Elastography.
Article in Annals of biomedical engineering, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
purposeSkeletal muscle is commonly modeled as a transversely isotropic medium; however, the behavior of its anisotropy under active loading remains insufficiently characterized. In this study, we used ultrasound time-harmonic elastography (THE) to quantify direction-dependent shear-wave speed (SWS) in the vastus lateralis (VL) muscle at rest and during low isometric contraction intensities.
methodsTwenty-six healthy adults (15 men, 11 women;
resultsAt rest, longitudinal SWS exceeded transverse SWS (
conclusionVL exhibited marked shear-wave anisotropy at rest that increased with low-level contraction intensities, indicating disproportionate stiffening along the fiber direction. THE provides a rapid, cost-effective, orientation-sensitive readout of muscle mechanics that may support studies of neuromuscular function and pathology.
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