Evidence map›Paper›PMID 42616207›Full record

Trial reportJournal of robotic surgery2026

Prevention of lymphedema after extended pelvic lymphadenectomy using diosmin, bromelain, melilotus, and hesperidin: results from a prospective randomized study (PRELYNE trial).

Francesca Montanaro, Greta Pettenuzzo, Sarah Malandra, Alessandro Veccia, Antonio Benito Porcaro, Alessandra Gozzo, Alberto Bianchi, Riccardo Rizzetto, Francesco Artoni, Sonia Costantino and 4 more

Abstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Journal of robotic surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Francesca Montanaro *University of Verona, Verona, Italy.
Greta Pettenuzzo *University of Verona, Verona, Italy.
Sarah Malandra *University of Verona, Verona, Italy.
Alessandro VecciaDepartment of Urology, Azienda Ospedaliera Universitaria Integrata Verona, Verona, Italy.
Antonio Benito PorcaroDepartment of Urology, Azienda Ospedaliera Universitaria Integrata Verona, Verona, Italy.
Alessandra GozzoDepartment of Urology, Azienda Ospedaliera Universitaria Integrata Verona, Verona, Italy.
Alberto BianchiDepartment of Urology, Azienda Ospedaliera Universitaria Integrata Verona, Verona, Italy.
Riccardo RizzettoDepartment of Urology, Azienda Ospedaliera Universitaria Integrata Verona, Verona, Italy.
Francesco ArtoniDepartment of Urology, Azienda Ospedaliera Universitaria Integrata Verona, Verona, Italy.
Sonia CostantinoDepartment of Urology, Azienda Ospedaliera Universitaria Integrata Verona, Verona, Italy.
Maria Angela CerrutoUniversity of Verona, Verona, Italy.
Riccardo BertoloUniversity of Verona, Verona, Italy. riccardogiuseppe.bertolo@univr.it.
Alessandro AntonelliUniversity of Verona, Verona, Italy.
Collaborators

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Extended pelvic lymph node dissection (ePLND) during robot-assisted radical prostatectomy (RARP) may impair lymphatic drainage, causing lower-limb and genital lymphedema with a potential negative impact on postoperative recovery and quality of life. This prospective randomized study evaluated whether an oral formulation containing diosmin, bromelain, melilotus, and hesperidin (Meliven Top

Indexed as

BromelainsDiosminHesperidinLymphedemaLymph Node ExcisionPlant ExtractsPostoperative ComplicationsProstatectomyRobotic Surgical ProceduresAgedHumansMaleMiddle AgedPelvisProspective StudiesProstatic NeoplasmsBromelainsDiosminHesperidinPlant Extracts

Identifiers

PMID42616207
PMCPMC13489991

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.