ReviewPediatric surgery international2026
Bibliometric analysis of congenital diaphragmatic hernia research models: evolution and insights from the past three decades.
Review in Pediatric surgery international, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
0 citing papers in PubMed.
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Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundResearch models of congenital diaphragmatic hernia (CDH) have evolved over time. We aimed to evaluate global research activities in CDH models using bibliometric analysis over the past three decades.
methodsStudies were retrieved from the Web of Science Core Collection (WoSCC) database between 1995 and 2024. Microsoft Excel, GraphPad Prism, and VOSviewer were applied to collect and analyze the bibliometric variables of this field.
resultsA total of 302 original publications from 21 countries were identified. The nitrofen rat model (n = 187) was used in most studies, followed by sheep (n = 44), and rabbit (n = 32) models. The use of mouse models increased over time. The USA leads with the highest number of publications (n = 78) and collaborations, and the Journal of Pediatric Surgery published most articles. Main publication topics were developmental biology, pulmonary hypertension and surgical techniques. "Congenital diaphragmatic hernia", "Nitrofen", and "Pulmonary hypoplasia" were the most frequent keywords, while "Sildenafil", "Mice", and "Endothelial" were recent research hotspots.
conclusionCDH research model has developed rapidly with increased collaborations and model diversity. Areas of interest varied, with a focus on developmental biology. Mouse models may gain importance to investigate genetic and molecular mechanisms of CDH.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.