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ArticleGraefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie2026

In vivo analysis of Schlemm's canal axial dimensions in children with juvenile idiopathic arthritis-associated uveitis.

Büşra Köse, Murat Günay, Adem Türk, Dilek Uzlu

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Article in Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

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4 authors.

Büşra KöseFaculty of Medicine, Department of Ophthalmology, Karadeniz Technical University, Trabzon, Türkiye, Turkey. busrakose-ktu@hotmail.com.ORCID http://orcid.org/0000-0001-9149-8083
Murat GünayFaculty of Medicine, Department of Ophthalmology, Karadeniz Technical University, Trabzon, Türkiye, Turkey.ORCID http://orcid.org/0000-0002-8874-1473
Adem TürkFaculty of Medicine, Department of Ophthalmology, Karadeniz Technical University, Trabzon, Türkiye, Turkey.ORCID http://orcid.org/0000-0002-9652-9317
Dilek UzluFaculty of Medicine, Department of Ophthalmology, Karadeniz Technical University, Trabzon, Türkiye, Turkey.ORCID http://orcid.org/0000-0002-7882-9076

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate Schlemm's canal (SC) axial dimensions using anterior segment optical coherence tomography (AS-OCT) in children with juvenile idiopathic arthritis-associated uveitis (JIA-U) and to investigate its relationship with uveitis-related prognostic factors.

methodsThis cross-sectional study included 60 eyes of 30 children with JIA-U and 33 eyes of 33 healthy pediatric controls. Comprehensive ophthalmic examination, biometric measurements, anterior chamber angle (ACA) assessment, and Schlemm's canal axial length (SCAL) measurements were performed using AS-OCT at nasal and temporal locations with right nasal SCAL used for the between-group comparison. Inter-eye, inter-location, and group comparisons were conducted. Subgroup and correlation analyses evaluated associations between SCAL and JIA-U-related clinical prognostic factors.

resultsNo significant differences were observed between right and left eyes or between nasal and temporal SCAL measurements in the JIA-U group. SCAL and ACA parameters did not differ significantly between the JIA-U and control groups (p > 0.05 for all). Correlation analysis revealed a location-specific significant negative association between uveitis duration and temporal SCAL in the right eye (r = - 0.489, p = 0.01).

conclusionsIn JIA-U children with well-controlled inflammation and intraocular pressure, SC axial dimensions appear to be largely preserved. A location-specific, exploratory inverse association was observed between uveitis duration and right temporal SCAL. These results warrant confirmation in larger, prospective studies before any conclusions regarding the impact of disease duration on aqueous outflow structures can be drawn.

Indexed as

Anterior segment optical coherence tomographyJuvenile idiopathic arthritisSchlemm's canalUveitis

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.