Evidence map›Paper›PMID 42615785›Full record

ArticleArquivos brasileiros de cardiologia2026

Cardiovascular Disease and Risk Factors in Women in Latin America and the Caribbean.

Claudio T Mesquita, Amalia Peix, Diana I Rodríguez, Karen A Dueñas-Criado, Claudia Gutiérrez-Villamil, Adriana Puente, Teresa Massardo, Isabel Berrocal, Andrea Astesiano, Roberto N Agüero and 14 more

Abstract read
In one paragraph

Article in Arquivos brasileiros de cardiologia, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Women's Cardiovascular Health: A Current Challenge.Arquivos brasileiros de cardiologia · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors.

Claudio T MesquitaHospital Universitário Antonio Pedro-Ebeserh (UFF), Niterói, RJ - Brasil.ORCID http://orcid.org/0000-0002-1466-9413
Amalia PeixInstituto de Cardiología y Cirugía Cardiovascular, La Habana - Cuba.ORCID http://orcid.org/0000-0001-5805-1810
Diana I RodríguezNuclear Medicine and Diagnostic Imaging Section, Division of Human Health, International Atomic Energy Agency, Vienna - Áustria.ORCID http://orcid.org/0000-0003-2243-1269
Karen A Dueñas-CriadoFundación Cardioinfantil-Instituto de Cardiología, Bogotá - Colômbia.ORCID http://orcid.org/0000-0001-7528-9011
Claudia Gutiérrez-VillamilFundación Cardioinfantil-Instituto de Cardiología, Bogotá - Colômbia.ORCID http://orcid.org/0000-0002-3748-7356
Adriana PuenteCentro Médico Nacional '20 de Noviembre', ISSSTE, Ciudad de México - México.ORCID http://orcid.org/0000-0002-5334-1429
Teresa MassardoUniversidad de Chile - Hospital Clínico, Santiago - Chile.ORCID http://orcid.org/0000-0002-2464-3188
Isabel BerrocalHospital San Juan de Dios - Caja Costarricense de Seguro Social, San José - Costa Rica.ORCID http://orcid.org/0000-0001-7130-4608
Andrea AstesianoFundación Escuela Medicina Nuclear (FUESMEN), Mendoza - Argentina.ORCID http://orcid.org/0000-0003-2953-9803
Roberto N AgüeroFundación Centro Diagnóstico Nuclear (FCDN), Buenos Aires - Argentina.ORCID http://orcid.org/0000-0001-7372-0912
Ryenne BañolasHospital Universitário Antonio Pedro-Ebeserh (UFF), Niterói, RJ - Brasil.ORCID http://orcid.org/0000-0002-7897-9648
Enrique HiplanHospital Base, Valdivia - Chile.ORCID http://orcid.org/0000-0002-8584-5234
Mayra SánchezHospital de Especialidades 'Carlos Andrade Marín', Quito - Equador.ORCID http://orcid.org/0000-0002-7214-9491
Ana Ma BarredaInstituto de Cardiología y Cirugía Cardiovascular, La Habana - Cuba.ORCID http://orcid.org/0000-0002-1519-4755
Vanessa V GómezHospital Oncológico del ISSS, San Salvador - El Salvador.ORCID http://orcid.org/0000-0002-3133-0358
Cynthia FernándezHospital María de Especialidades Pediátricas, Tegucigalpa - Honduras.
Silvia PortilloInstituto Nacional Cardiopulmonar, Tegucigalpa - Honduras.
Yariela HerreraHospital Santo Tomás, Ciudad de Panamá - Panamá.ORCID http://orcid.org/0009-0003-6863-611X
Aurelio MendozaInstituto Nacional Cardiovascular INCOR, Lima - Perú.ORCID http://orcid.org/0000-0001-8091-5179
Miguel KapitanHospital Italiano, Montevideo - Uruguai.ORCID http://orcid.org/0000-0002-0011-3158
Carlos CastellanosHospital Dr. Carlos Arvelo, Caracas - Venezuela.ORCID http://orcid.org/0009-0003-1620-0314
Enrique Estrada-LobatoNuclear Medicine and Diagnostic Imaging Section, Division of Human Health, International Atomic Energy Agency, Vienna - Áustria.ORCID http://orcid.org/0000-0002-2597-8609
Diana PaezNuclear Medicine and Diagnostic Imaging Section, Division of Human Health, International Atomic Energy Agency, Vienna - Áustria.ORCID http://orcid.org/0000-0001-9268-0979
Giovane LHospital Universitário Antonio Pedro-Ebeserh (UFF), Niterói, RJ - Brasil.ORCID http://orcid.org/0009-0001-1083-2332

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCardiovascular disease (CVD) remains the leading cause of death among women in Latin America and the Caribbean (LAC), with ischemic heart disease as the primary contributor. Despite this burden, women's health programs in the region have traditionally prioritized cancer prevention, often neglecting CVD.

objectiveTo analyze the burden of CVD and the distribution of cardiovascular risk factors among women in LAC, highlighting sex-related differences and regional disparities.

methodsThis study analyzed epidemiological data on CVD mortality and cardiovascular risk factors across LAC countries, including behavioral, metabolic, and female-specific risk factors, and conducted comparisons with selected countries outside the region.

resultsWomen in LAC showed a higher prevalence of sedentary lifestyle, dyslipidemia, elevated fasting blood glucose, and overweight/obesity, whereas smoking was more frequent among men. Female-specific risk factors - such as teenage pregnancy, preterm birth, gestational diabetes, and hypertensive disorders of pregnancy - were highly prevalent yet under-recognized, largely shaped by socioeconomic determinants. In 2021, COVID-19 temporarily surpassed ischemic heart disease and stroke as the leading cause of death in the Americas (176.7 deaths per 100,000 population), highlighting the vulnerability of women with underlying cardiometabolic risk. Premature CVD mortality varied widely, with the highest female probabilities of death between ages 30 and 70 observed in Haiti (21.9%) and Guyana (15.2%), associated with poorly controlled hypertension and elevated cholesterol, respectively. In contrast, Canada showed the lowest premature mortality (1.7%), reflecting stronger healthcare systems and lower prevalence of metabolic risk factors.

conclusionCVD remains the leading cause of mortality among women in LAC, marked by substantial regional disparities and a significant burden of both traditional and female-specific risk factors. These findings highlight the urgent need for sex-specific, context-sensitive strategies that integrate cardiovascular prevention into comprehensive women's health policies, moving beyond cancer-centered approaches.

Indexed as

Cardiovascular DiseasesHeart Disease Risk FactorsWomen's HealthAdultAgedCaribbean PeopleCaribbean RegionCentral American PeopleFemaleHumansLatin AmericaMaleMiddle AgedPrevalenceRisk FactorsSex Factors

Identifiers

PMID42615785
PMCPMC13668458

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.