ArticleArquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery2026
Management, evolution and risk factors of bile leaks after subtotal cholecystectomies: a cohort study in Quito, Equador.
Article in Arquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundLaparoscopic subtotal cholecystectomy is indicated for severe cholecystitis; however, it may lead to complications, including postoperative bile fistulas.
aimsTo evaluate the management, evolution, and risk factors associated with bile fistulas after laparoscopic subtotal cholecystectomy in a hospital in Quito from January 2019 to June 2022.
methodsA cross-sectional analytical study with a quantitative approach was conducted. A retrospective review of medical records of patients who underwent laparoscopic subtotal cholecystectomy (n=256) was performed. The dependent variable was the occurrence of bile fistulas, while independent variables included sociodemographic data (age, sex) and clinical factors such as comorbidities, nutritional status, cholecystitis severity (Parkland classification), surgical planning, type of cholecystectomy, anesthetic risk (American Society of Anesthesiologists; ASA I-IV), surgical time, intraoperative complications, time of fistula onset, evolution, and postoperative complications.
resultsThe incidence of postoperative fistulas was 12.9% (n=33). Management strategies included drainage (69.7%) and endoscopic retrograde cholangiopancreatography (ERCP) (30.3%). Spontaneous closure occurred in 60.6%, while 30.3% required therapeutic ERCP and 9.1% needed reoperation. Significant risk factors included surgical time >105 minutes (relative risk [RR]: 2.06; 95% confidence interval [CI] 1.04-4.08), type A cholecystectomy (RR 2.19; 95%CI 1.05-4.57), and choledocholithiasis (RR 2.5; 95%CI 1.34-4.67). Logistic regression confirmed surgical time (odds ratio [OR]: 2.6; 95%CI 1.2-5.8) and choledocholithiasis (OR 3.3; 95%CI 1.4-3.9) as significant predictors (p<0.05).
conclusionsThe incidence of postoperative fistulas observed was comparable to previous reports in the literature, highlighting the importance of early identification and appropriate management. CENTRAL MESSAGE: Type B subtotal cholecystectomies were associated with bile leaks, as were the presence or history of choledocholithiasis and prolonged surgical times, exceeding 105 minutes. Bile leaks were not related to whether a prior ERCP or sphincterotomy were performed, nor to the presence of biliary stents. PERSPECTIVES: There is currently no standardization regarding the optimal timing for ERCP for bile leaks or the amount of bile leakage that should prompt the procedure. A standardized prospective study could help establish evidence-based management criteria.
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