ArticleInternational journal of dentistry2026
Comparative Assessment of Five Decalcification Methods for Human Dental Tissue: An Ex Vivo Laboratory Study.
Article in International journal of dentistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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Who cites it
1 citing paper in PubMed.
- Comparative Assessment of Five Decalcification Methods for Human Dental Tissue: An Ex Vivo Laboratory Study.International journal of dentistry · 2026Article
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10 authors.
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Abstract
Background: Histological examination of human teeth is essential for the diagnosis of developmental anomalies, odontogenic lesions, and other dental pathologies. However it remains technically challenging because highly mineralized tissues require extensive processing before thin sections suitable for microscopic evaluation can be obtained. This study aimed to identify a decalcification protocol suitable for routine dental pathology by balancing rapid processing with high-quality tissue preservation. To achieve this, we compared five commonly used decalcification protocols using complementary histological and spectroscopic analyses. Methods: Forty-nine human teeth were decalcified using one of the five investigated agents: HNO Results: Decalcification efficiency differed markedly among the tested agents. HNO Conclusions: By integrating histology with LIBS analysis, this study demonstrates that decalcifying agents differ substantially in their decalcification speed, tissue preservation, and mineral removal profiles. Notably, 5% HNO
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