Evidence map›Paper›PMID 42614742›Full record

ArticleMedicine international

Ultrasonographic diagnosis and laparoscopic management of an interstitial ectopic pregnancy: A case report and literature review.

Fani-Niki Varra, Apostolos Fasoulopoulos, Vasiliki Sfika, Evdokia Sfiniadaki, Viktoria-Konstantina Varra, Michail Varras

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Article in Medicine international. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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0 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Fani-Niki VarraDepartment of Pharmacy, School of Health Sciences, Frederick University, Nicosia 1036, Cyprus.
Apostolos FasoulopoulosFourth Department of Obstetrics and Gynecology, 'Elena Venizelou' General and Maternity Hospital, 11521 Athens, Greece.
Vasiliki SfikaDepartment of Ultrasound, 'Elena Venizelou' General and Maternity Hospital, 11521 Athens, Greece.
Evdokia SfiniadakiFourth Department of Obstetrics and Gynecology, 'Elena Venizelou' General and Maternity Hospital, 11521 Athens, Greece.
Viktoria-Konstantina VarraDepartment of Pharmacy, School of Health Sciences, National and Kapodistrian University of Athens, 15771 Athens, Greece.
Michail VarrasFourth Department of Obstetrics and Gynecology, 'Elena Venizelou' General and Maternity Hospital, 11521 Athens, Greece.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Interstitial ectopic pregnancy is a rare yet potentially life-threatening type of ectopic gestation, representing ~2-4% of all ectopic pregnancies. As implantation occurs within the interstitial portion of the fallopian tube, the clinical presentation is often delayed, and the risk of a catastrophic hemorrhage is increased in the event that rupture occurs due to its intramural location. Early and accurate diagnosis with high-resolution transvaginal ultrasonography (TVUS) is thus essential to improve outcomes and preserve fertility. The present case report describes the clinical course of a 35-year-old woman (gravida 2, para 1) who presented with prolonged vaginal bleeding and recent-onset hypogastric pain. Serum β-human chorionic gonadotropin (β-hCG) levels plateaued just below 1,000 mIU/ml. TVUS revealed an empty uterine cavity, a thin endometrium and an eccentrically located, mixed-echogenicity mass within the right uterine cornu, clearly separate from the endometrial cavity. Key sonographic findings included the interstitial line sign, marked asymmetric thinning of the myometrial mantle surrounding the gestational sac to <5 mm and the absence of an adjacent endometrium. Color Doppler imaging demonstrated mild peripheral vascularity. Emergency laparoscopy confirmed an unruptured interstitial pregnancy lateral to the right round ligament. A laparoscopic wedge resection of the interstitial segment was successfully performed, with local vasopressin administration to minimize intraoperative blood loss. The post-operative course of the patient was uneventful, with a rapid decline in β-hCG levels and no requirement for adjuvant methotrexate therapy. On the whole, the present case report underscores the critical role of high-resolution TVUS in the early diagnosis of interstitial pregnancy, and highlights the safety and efficacy of minimally invasive laparoscopic excision in hemodynamically stable patients with unruptured interstitial gestations. Early recognition and individualized surgical management are essential for optimizing clinical outcomes and preserving fertility in this rare condition.

Indexed as

ectopic pregnancyinterstitial line signinterstitial pregnancyoperative laparoscopytransvaginal ultrasonographyβ-human chorionic gonadotropin levels

Identifiers

PMID42614742
PMCPMC13483164

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