Evidence map›Paper›PMID 42614257›Full record

Trial reportFrontiers in psychology2026

Immersive virtual reality as an auxiliary intervention for college students with mild-to-moderate depressive symptoms: a pilot randomized controlled trial.

Zhiquan Xie, Qisheng Liang, Li Xu, Jiequn Xie, Shaohao Xie, Liqin Zou

Abstract readClinical Trial
In one paragraph

Trial report in Frontiers in psychology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Zhiquan XieZhaoqing Medical College, Zhaoqing, China.
Qisheng LiangThe Third People's Hospital of Zhaoqing, Zhaoqing, China.
Li XuThe Third People's Hospital of Zhaoqing, Zhaoqing, China.
Jiequn XieQingcheng District People's Hospital of Qingyuan, Qingyuan, China.
Shaohao XieThe People's Hospital of Dinghu District, Zhaoqing, China.
Liqin ZouZhaoqing Medical College, Zhaoqing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Mild-to-moderate depression is highly prevalent among Chinese college students, with conventional treatments having limitations. This study aimed to explore psychological benefits brought by a standardized immersive virtual reality (IVR) game intervention. Methods: This pilot randomized controlled trial enrolled 70 participants split into intervention and control groups; all obtained routine psychological guidance, and the intervention group received a standardized IVR program. Results: Significant group-by-time interactions were detected for negative affect (NA) and the Pittsburgh Sleep Quality Index (PSQI, Conclusion: This IVR program acts as a targeted adjunctive tool to reduce negative affect for college students. No significant improvements in core clinical depression severity (HAMD-17) were detected. Broader clinical antidepressant effects cannot be inferred from the present exploratory findings. Clinical trial registration: https://www.chictr.org.cn, identifier ChiCTR2400093178.

Indexed as

college studentsdepressionimmersive virtual reality (IVR)pilot randomized controlled trialpsychological intervention

Identifiers

PMID42614257
PMCPMC13481359

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.