Evidence map›Paper›PMID 42614219›Full record

ReviewFrontiers in molecular biosciences2026

Isoprostanes as biomarkers of oxidative stress across human diseases and skin pathologies.

Aleksandra Okuniewska, Narcyz Knap, Ewa Kulpińska, Michał Woźniak, Alicja Dębska-Ślizień, Beata Imko-Walczuk

Abstract readReview
In one paragraph

Review in Frontiers in molecular biosciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Aleksandra OkuniewskaDepartment of Medical Chemistry, Medical University of Gdansk, Gdańsk, Poland.
Narcyz KnapDepartment of Medical Chemistry, Medical University of Gdansk, Gdańsk, Poland.
Ewa KulpińskaDermatology and Venereology Outpatient Clinic, Copernicus, Independent Public Healthcare Centre, Gdańsk, Poland.
Michał WoźniakDepartment of Medical Chemistry, Medical University of Gdansk, Gdańsk, Poland.
Alicja Dębska-ŚlizieńDepartment of Nephrology Transplantology and Internal Diseases, Medical University of Gdańsk, Gdańsk, Poland.
Beata Imko-WalczukDermatology and Venereology Outpatient Clinic, Copernicus, Independent Public Healthcare Centre, Gdańsk, Poland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oxidative stress (OS), resulting from an imbalance between reactive oxygen species (ROS) production and antioxidative defenses, is connected with various diseases, including cancer. Isoprostanes (IsoPs), derived from peroxidation of polyunsaturated fatty acids (PUFAs), serve as reliable biomarkers of OS. This review collects knowledge about IsoPs as indicators of OS, focusing on their association with various diseases, among others different types of cancer, and also skin disorders. Roughly 3 decades ago IsoPs were characterized

Indexed as

biomarkerscancerhuman diseaseisoprostanesoxidative stressskin cancerskin pathologiestransplantation

Identifiers

PMID42614219
PMCPMC13481243

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.