Trial reportFrontiers in neurology2026
Effect of low-frequency repetitive transcranial magnetic stimulation combined with abdominal acupuncture on lower limb motor function and balance in post-stroke hemiplegia: a randomized controlled trial.
Trial report in Frontiers in neurology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Post-stroke hemiplegia frequently results in lower limb motor dysfunction and impaired balance, leading to reduced independence in activities of daily living. Repetitive transcranial magnetic stimulation (rTMS) and abdominal acupuncture (AA) are both used in rehabilitation, but evidence on their combined effect remains limited. This study evaluated the efficacy and safety of low-frequency rTMS combined with AA in patients with post-stroke hemiplegia. Methods: In this assessor-blind randomized controlled trial, 108 patients with post-stroke hemiplegia and lower limb dysfunction were randomly assigned (1:1:1) to a control group (conventional rehabilitation), an AA group (rehabilitation plus abdominal acupuncture), or a combined group (rehabilitation plus AA and low-frequency rTMS). All interventions were administered for 8 weeks. Outcomes were assessed at baseline, 4 weeks, and 8 weeks. The primary outcomes included lower limb motor function measured by the Fugl-Meyer Assessment of Lower Extremity (FMA-LE), balance assessed by the Berg Balance Scale (BBS), and activities of daily living evaluated using the Modified Barthel Index (MBI). Adverse events were recorded to assess safety. Results: All groups showed significant improvement in FMA-LE, BBS, and MBI scores at 4 and 8 weeks compared with baseline (all Conclusion: Low-frequency rTMS combined with abdominal acupuncture significantly improves lower limb motor function, balance, and activities of daily living in patients with post-stroke hemiplegia, with a favorable safety profile. This combined approach may offer an effective strategy for enhancing rehabilitation outcomes. Clinical trial registration: https://itmctr.ccebtcm.org.cn, identifer ITMCTR2026001195.
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