ArticleFrontiers in cardiovascular medicine2026
Association of the triglyceride-glucose index and phlegm-dampness constitution with subclinical carotid atherosclerosis in overweight and obese individuals.
Article in Frontiers in cardiovascular medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Abstract
Objective: This study aims to investigate the association between the triglyceride-glucose (TyG) index and Phlegm-dampness constitution (PDC), as well as their joint association, on subclinical carotid atherosclerosis (SCAS) in an overweight and obese population. Methods: In this cross-sectional study, 217 overweight or obese participants were enrolled. The TyG index was categorized at the median into high and low TyG groups, and a four-category joint exposure variable was developed based on PDC status. Multivariable logistic regression was employed to assess the relationship between joint exposure and SCAS, with a stratified analysis conducted by PDC. Results: SCAS was identified in 67 of 217 participants (30.9%). The TyG index (AUC 0.681) demonstrated superior performance compared to HOMA-IR (0.585) and BMI (0.515) in distinguishing SCAS. The AUC increased from 0.704 (base model: age, sex, BMI) to 0.779 after adding the TyG index (DeLong Conclusion: The coexistence of a high TyG index and PDC was associated with markedly higher odds of SCAS. The finding that the TyG-SCAS association appeared stronger in the PDC subgroup is exploratory and requires validation in larger prospective studies.
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