ArticleFrontiers in oral health2026
Refrigerated storage of L-PRF membranes: anti-bacterial activity, cytokine release, and
Article in Frontiers in oral health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Aims: This Methods: L-PRF membranes obtained from 8 volunteers were stored in L-PRF exudate at 4°C for 1, 2, or 4 weeks. Their antibacterial properties against the main periodontal pathogens, release levels of key growth factors and inflammatory cytokines, and regenerative effects on human oral keratinocytes (HOKs) were compared to fresh L-PRF. Results: The inhibitory effects of L-PRF exudate varied among the tested pathogens and gradually decreased during storage. Growth factors released from L-PRF membranes exhibited different degradation kinetics, with VEGF demonstrating an early reduction within the first week, whereas PDGF-AB and TGF- Conclusion: Refrigerated storage preserved some L-PRF functions for up to 4 weeks in this
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.