ArticleMedical physics2026
Develop a novel non-coplanar trajectory optimization algorithm for an efficient 4pi spot-scanning proton Arc (SPArc
Article in Medical physics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundThe degree of freedom has been recognized as a key factor in particle beam therapy, such as improving the dose conformity and linear energy transfer distributions. Therefore, proton arc therapy has drawn significant interest in the Society of Radiation Oncology as a potentially efficient and optimal treatment option for cancer patients. However, state-of-the-art spot-scanning proton arc therapy (SPArc) still relies on single or dual- co-planar arc trajectories, which limits its capacity to advance the treatment outcome further. There is an urgent need to explore particle beam therapy's full potential via 4pi. PURPOSE: This study aims to develop the first 4pi arc optimization algorithm that searches for efficient arc trajectories in 4pi space, explores the potential dosimetric improvements, and demonstrates its feasibility through simulation.
methodDynamic Programming, originally from control theory, was translated into this new concept of the 4pi SPArc optimization algorithm (SPArc
resultThe new SPArc
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