ArticleClinical and translational allergy2026
ARIA-EAACI 2025: Person-Centred, Digitally Enabled and Artificial Intelligence-Assisted Change Management in Airway Diseases: An OECD Best Practice for Integrated Care for Chronic Diseases.
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156 authors.
Jean BousquetInstitute of Allergology, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.ORCID https://orcid.org/0000-0002-4061-4766
Bernardo Sousa-PintoMEDCIDS - Department of Community Medicine, Information and Health Decision Sciences, Faculty of Medicine, University of Porto, Porto, Portugal.ORCID https://orcid.org/0000-0002-1277-3401
Mohamed H ShamjiNational Heart and Lung Institute, Imperial College, London, UK.
Maria J TorresAllergy Unit, Regional University Hospital of Málaga, Málaga University, ARADyAL, Málaga, Spain.
Ludger KlimekDepartment of Otolaryngology, Head and Neck Surgery, Universitätsmedizin Mainz, Mainz, Germany.ORCID https://orcid.org/0000-0002-2455-0192
Holger J SchünemannFraunhofer Institute for Translational Medicine and Pharmacology ITMP, Immunology and Allergology, Berlin, Germany.ORCID https://orcid.org/0000-0003-3211-8479
Mario Morais-AlmeidaAllergy Center, CUF Descobertas Hospital, Lisbon, Portugal.
Rafael José VieiraMEDCIDS - Department of Community Medicine, Information and Health Decision Sciences, Faculty of Medicine, University of Porto, Porto, Portugal.ORCID https://orcid.org/0000-0003-1834-3055
Alkis TogiasDivision of Allergy, Immunology, and Transplantation (DAIT), National Institute of Allergy and Infectious Diseases, NIH, Bethesda, Maryland, USA.
Boleslaw SamolinskiDepartment of Prevention of Environmental Hazards, Allergology and Immunology, Medical University of Warsaw, Warsaw, Poland.
Arunas ValiulisInstitute of Clinical Medicine, Medical Faculty of Vilnius University, Vilnius, Lithuania.
Siân WilliamsInternational Primary Care Respiratory Group IPCRG, Edinburgh, UK.
Oliver PfaarSection of Rhinology and Allergy, Department of Otorhinolaryngology, Head and Neck Surgery, University Hospital Marburg, Philipps-Universität Marburg, Marburg, Germany.
Torsten ZuberbierInstitute of Allergology, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.ORCID https://orcid.org/0000-0002-1466-8875
Anna BedbrookARIA (Allergic Rhinitis and its Impact on Asthma), Montpellier, France.
Wienczyslawa CzarlewskiARIA (Allergic Rhinitis and its Impact on Asthma), Montpellier, France.
Maryam Ali Al-NesfAdult Allergy and Immunology Division, Hamad Medical Corporation, Doha, Qatar.ORCID https://orcid.org/0000-0001-9354-0214
Rita AmaralMEDCIDS - Department of Community Medicine, Information and Health Decision Sciences, Faculty of Medicine, University of Porto, Porto, Portugal.
Josep M AntoUniversitat Pompeu Fabra (UPF), Barcelona, Spain.
Antonio BognanniDepartment of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Ontario, Canada.ORCID https://orcid.org/0000-0003-0128-903X
Luisa BrussinoDepartment of Medical Sciences, University of Torino, Torino, Italy.
Alvaro A CruzFundacao ProAR and (Faculdade de Medicina da) Universidade Federal da Bahia, Salvador, Bahia, Brazil.ORCID https://orcid.org/0000-0002-7403-3871
Violeta KvedarieneFaculty of Medicine, Institute of Clinical Medicine, Clinic of Chest Diseases and Allergology, Vilnius University, Vilnius, Lithuania.
Habib DouaguiService de Pneumo-Allergologie, Centre Hospitalo-Universitaire de Béni-Messous, Algiers, Algeria.
Nikolaos G PapadopoulosAllergy Department, 2nd Pediatric Clinic, University of Athens, Athens, Greece.
G Walter CanonicaDepartment of Biomedical Sciences, Humanitas University, Milan, Italy.ORCID https://orcid.org/0000-0001-8467-2557
Ivan Cherrez-OjedaUniversidad Espíritu Santo, Samborondón, Ecuador.ORCID https://orcid.org/0000-0002-1610-239X
Mark DykewiczSection of Allergy and Immunology, Saint Louis University School of Medicine, Saint Louis, Missouri, USA.
Bilun GemiciogluDepartment of Pulmonary Diseases, Cerrahpaşa Faculty of Medicine, Istanbul University-Cerrahpaşa, Istanbul, Turkey.ORCID https://orcid.org/0000-0001-5953-4881
Mattia GiovanniniAllergy Unit, Meyer Children's Hospital IRCCS, Florence, Italy.ORCID https://orcid.org/0000-0001-9568-6882
Brigita GradauskieneDepartment of Immunology and Allergology, Lithuanian University of Health Sciences, Kaunas, Lithuania.
Tari HaahtelaSkin and Allergy Hospital, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.
Cristina JacomelliAssociazione Respiriamo Insieme, Padova, Italy.
Tuomas JarttiDepartment of Pediatrics and Adolescent Medicine, Turku University Hospital, University of Turku, Turku, Finland.
Miloš JeseňákDepartment of Paediatrics and Adolescent Medicine, Jessenius Faculty of Medicine, Institute of Clinical Immunology and Medical Genetics, University Hospital Martin, Martin, Slovakia.
Piotr KunaDivision of Internal Medicine, Asthma and Allergy, Barlicki University Hospital, Medical University of Lodz, Lodz, Poland.
Désirée E Larenas-LinnemannCenter of Excellence in Asthma and Allergy, Médica Sur Clinical Foundation and Hospital, Mexico City, Mexico.ORCID https://orcid.org/0000-0002-5713-5331
Amir H A LatiffAllergy & Immunology Centre, Pantai Hospital Kuala Lumpur, Kuala Lumpur, Malaysia.
Bryan MartinDepartment of Otolaryngology, Division of Allergy & Immunology, Medicine and Pediatrics, The Ohio State University, Columbus, Ohio, USA.
Yousser MohammadNational Center for Research in Chronic Respiratory Diseases, Collaborating with WHO-EMRO Tishreen University School of Medicine, Latakia, Syria.
Kari NadeauDepartment of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.ORCID https://orcid.org/0000-0002-2146-2955
Elizabete NunesFaculty of Medicine, Eduardo Mondlane University, Maputo, Mozambique.
Ken OhtaJapan Antituberculosis Association (JATA) Fukujuji Hospital, Tokyo, Japan.
Martial OuédraogoDepartment of Pulmonology, Yalgado Ouédraogo University Hospital Center, Ouagadougou, Burkina Faso.
Padukudru A MaheshDepartment of Respiratory Medicine, JSS Medical College, JSS Academy of Higher Education and Research, Mysuru, India.ORCID https://orcid.org/0000-0003-1632-5945
Isabella Pali-SchölllDepartement of Biological Sciences and Pathophysiology, University of Veterinary Medicine, Vienna, Austria.
Ana Margarida PereiraMEDCIDS - Department of Community Medicine, Information and Health Decision Sciences, Faculty of Medicine, University of Porto, Porto, Portugal.ORCID https://orcid.org/0000-0002-5468-0932
Frederico S RegateiroAllergy and Clinical Immunology Department, Hospitais da Universidade de Coimbra, Unidade Local de Saúde de Coimbra, Coimbra, Portugal.ORCID https://orcid.org/0000-0002-6332-3056
Nicolas RochePneumologie, AP-HP Centre Université de Paris Cité, Hôpital Cochin, Paris, France.
Mikhail SofievFinnish Meteorological Institute (FMI), Helsinki, Finland.
Luis Taborda-BarataFaculty of Health Sciences, RISE-Health, University of Beira Interior, Covilhã, Portugal.
Charlotte Suppli UlrikDepartment of Respiratory Medicine, Copenhagen University Hospital-Hvidovre, Copenhagen, Denmark.ORCID https://orcid.org/0000-0001-8689-3695
Sanna K Toppila-SalmiDepartment of Otorhinolaryngology, University of Eastern Finland, Kuopio, Finland.ORCID https://orcid.org/0000-0003-0890-6686
Marylin Valentin RostanPediatrics, Allergy & Immunology, Latín American Society of Allergy, Asthma & Immunology (SLAAi), Montevideo, Uruguay.
Leticia de Las VecillasDepartment of Allergy, Hospital La Paz, Institute for Health Research (IdiPAZ), Madrid, Spain.ORCID https://orcid.org/0000-0003-4969-5678
Maria Teresa VenturaUniversity of Bari Medical School, Bari, Italy.
Giovanni ViegiPulmonary Environmental Epidemiology Unit, CNR Institute of Clinical Physiology, Pisa, Italy.
De Yun WangDepartment of Otolaryngology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.ORCID https://orcid.org/0000-0002-0909-2963
He ZhangDepartment of Otolaryngology-Head and Neck Surgery, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Luo ZhangDepartment of Otolaryngology-Head and Neck Surgery, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.ORCID https://orcid.org/0000-0002-0910-9884
Giorgio CiprandiCasa di Cura Villa Montallegro, Genova, Italy.ORCID https://orcid.org/0000-0001-7016-8421
Juan Carlos IvancevichServicio de Alergia e Immunologia, Clinica Santa Isabel, Buenos Aires, Argentina.
Nikolai KhaltaevGlobal NCD Platform, Geneva, Switzerland.
Olga LourençoRISE-Health, Department of Medical Sciences, Faculty of Health Sciences, University of Beira Interior, Covilhã, Portugal.ORCID https://orcid.org/0000-0002-8401-5976
Lucas LeemannDepartment of Political Science, University of Zurich, Zurich, Switzerland.
Marine SavouréUniversitat Pompeu Fabra (UPF), Barcelona, Spain.ORCID https://orcid.org/0000-0003-3220-8175
Juan Jose Yepes-NuñezSchool of Medicine, Universidad de los Andes, Bogotá, DC, Colombia.
Arzu YorganciogluDepartment of Pulmonary Diseases, Faculty of Medicine, Celal Bayar University, Manisa, Turkey.
Baharudin AbdullahDepartment of Otorhinolaryngology, Head and Neck Surgery, School of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian, Kelantan, Malaysia.ORCID https://orcid.org/0000-0001-9138-9215
Mona Al-AhmadMicrobiology Department, College of Medicine, Kuwait University, Kuwait City, Kuwait.
Julijana AsllaniDepartment of Internal Medicine, University of Medicine, Tirana, Albania.ORCID https://orcid.org/0009-0003-1493-7101
Karl-C BergmannInstitute of Allergology, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.ORCID https://orcid.org/0009-0003-2924-2046
Jonathan A BernsteinDivision of Immunology, Allergy and Rheumatology, Department of Medicine, University of Cincinnati, College of Medicine, Cincinnati, Ohio, USA.
Michael S BlaissDepartment of Pediatrics, Medical College of Georgia at Augusta University, Augusta, Georgia, USA.
Fulvio BraidoRespiratory and Allergy Clinic, IRCCS - Policlinico San Martino, Genova, Italy.
Pedro Carreiro-MartinsCHRC, LA-REAL, NOVA Medical School, NMS, Universidade NOVA de Lisboa, Lisboa, Portugal.
Lorenzo CecchiAllergy and Clinical Immunology Unit, San Giovanni di Dio Hospital, Florence, Italy.ORCID https://orcid.org/0000-0002-0658-2449
Antonio F M GiulianoClinica Medica 'A. Murri', Department of Preventive and Regenerative and Ionian Area (DiMePre-J), University of Bari "Aldo Moro", AOUC Policlinico Hospital, Bari, Italy.ORCID https://orcid.org/0000-0002-9345-5156
George ChristoffBulgarian Alliance for Clinical and Translational Allergy, Sofia, Bulgaria.
Ieva CiruleLatvian Association of Allergists, University Children Hospital, Riga, Latvia.
Jaime Correia-de-SousaLife and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Braga, Portugal.ORCID https://orcid.org/0000-0001-6459-7908
Elisio M CostaCINTESIS@RISE, Biochemistry Lab, Faculty of Pharmacy and Competence Center on Active and Healthy Ageing, University of Porto, Porto, Portugal.
Biljana CvetkovskiWoolcock Institute of Medical Research, Sydney, New South Wales, Australia.
Stefano Del GiaccoDepartment of Medical Sciences and Public Health and Unit of Allergy and Clinical Immunology, University Hospital "Duilio Casula", University of Cagliari, Cagliari, Italy.
Philippe DevillierVIM Suresnes, UMR 0892, Pôle des Maladies des Voies Respiratoires, Hôpital Foch, Université Paris-Saclay, Suresnes, France.
Dejan DokicMedical Faculty Skopje, University Clinic of Pulmology and Allergy, Skopje, North Macedonia.ORCID https://orcid.org/0000-0001-6950-5291
Maia GotuaCenter of Allergy and Immunology, and Georgian Academy of Allergy, Asthma, and Clinical Immunology, Tbilisi, Georgia.
Maria Antonieta GuzmanImmunology and Allergy Division, Clinical Hospital, University of Chile, Santiago, Chile.
Elham HossnyPediatric Allergy, Immunology and Rheumatology Unit, Children's Hospital, Ain Shams University, Cairo, Egypt.
Tomohisa IinumaDepartment of Otorhinolaryngology, Chiba University, Chiba, Japan.
Carla IraniDepartment of Internal Medicine and Infectious Diseases, St Joseph University, Hotel Dieu de France Hospital, Beirut, Lebanon.
Zhanat IspayevaDepartment of Allergology and Clinical Immunology, Kazakhstan Association of Allergology and Clinical Immunology, Kazakh National Medical University, Almaty, Kazakhstan.
Kaja JulgeInstitute of Clinical Medicine, Tartu University, Children's Clinic, Tartu, Estonia.
Igor KaidashevPoltava State Medical University, Poltava, Ukraine.ORCID https://orcid.org/0000-0002-4708-0859
Kazi S BennoorDepartment of Respiratory Medicine, National Institute of Diseases of the Chest and Hospital, Dhaka, Bangladesh.
Helga KraxnerDepartment of Otorhinolaryngology, Head and Neck Surgery, Semmelweis University, Budapest, Hungary.
Inger KullDepartment of Clinical Science and Education, Södersjukhuset, Karolinska Institutet, Stockholm, Sweden.ORCID https://orcid.org/0000-0001-6096-3771
Marek KulusDepartment of Pediatric Respiratory Diseases and Allergology, Medical University of Warsaw, Warsaw, Poland.
Maciej KupczykDivision of Internal Medicine, Asthma and Allergy, Barlicki University Hospital, Medical University of Lodz, Lodz, Poland.
Andriy KurchenkoDepartment of Clinical and Laboratory Immunology, Allergology and Medical Genetics, Bogomolets National Medical University, Kyiv, Ukraine.
Xin LuoDepartment of Otolaryngology-Head and Neck Surgery, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Stefania La GruttaInstitute of Translational Pharmacology (IFT) - National Research Council (CNR), Palermo, Italy.
Lan Le Thi TuyetAsthma, COPD Outpatient Care Unit, University Medical Center, Ho Chi Minh City, Vietnam.
Michael MakrisAllergy Unit "D Kalogeromitros", 2nd Department of Dermatology and Venereology, National & Kapodistrian University of Athens, "Attikon" University Hospital, Athens, Greece.
Branislava MilenkovicFaculty of Medicine, Clinic for Pulmonary Diseases, Clinical Center of Serbia, University of Belgrade, Serbian Association for Asthma and COPD, Belgrade, Serbia.
Neven MiculinicCroatian Pulmonary Society, Zagreb, Croatia.
Sang Min LeeDivision of Respiratory Disease and Allergy, Department of Internal Medicine, Dankook University College of Medicine, Cheonan, South Korea.
Stephen MontefortDepartment of Medicine, Faculty of Medicine and Surgery, University of Malta, Msida, Malta.
André MoreiraEPIUnit, Institute of Public Health, University of Porto, Porto, Portugal.
Joaquim MullolRhinology Unit & Smell Clinic, ENT Department, Hospital Clínic, Barcelona, Spain.
Rachel NadifInserm, Equipe d'Epidémiologie Respiratoire Intégrative, CESP, Villejuif, France.
Alla NakonechnaImperial College Healthcare NHS Trust, London, UK.
Hugo E NeffenCenter of Allergy, Immunology and Respiratory Diseases, Santa Fe, Argentina.
Stefania NicolaDepartment of Medical Sciences, University of Torino, Torino, Italy.
Marek NiedoszytkoDepartment of Allergology, Medical University of Gdańsk, Gdansk, Poland.
Dieudonné NyembueENT Department, University Hospital of Kinshasa, Kinshasa, Democratic Republic of the Congo.
Robyn E O'HehirAllergy, Asthma and Clinical Immunology, Alfred Health, Department of Immunology, School of Translational Medicine, Monash University, Melbourne, Victoria, Australia.
Ismail OgulurSwiss Institute of Allergy and Asthma Research (SIAF), University of Zurich, Davos, Switzerland.ORCID https://orcid.org/0000-0001-8282-7762
Yoshitaka OkamotoChiba University Hospital, Chiba, Japan.
Markus OllertDepartment of Infection and Immunity, Luxembourg Institute of Health, Esch-sur-Alzette, Luxembourg.ORCID https://orcid.org/0000-0002-8055-0103
Heidi OlzeDepartment of Otorhinolaryngology, Charité - University Medical Center Berlin, Berlin, Germany.
Oscar PalomaresDepartment of Biochemistry and Molecular Biology, School of Chemistry, Complutense University of Madrid, Madrid, Spain.ORCID https://orcid.org/0000-0003-4516-0369
Petr PanznerDepartment of Immunology and Allergology, Faculty of Medicine in Pilsen, Charles University, Prague, Czech Republic.ORCID https://orcid.org/0000-0002-1291-450X
Hae-Sim ParkDepartment of Allergy and Clinical Immunology, Ajou University School of Medicine, Suwon, South Korea.ORCID https://orcid.org/0000-0003-2614-0303
Vincenzo PatellaDivision of Allergy and Clinical Immunology, Department of Medicine, 'Santa Maria della Speranza' Hospital, Salerno, Italy.
Ruby PawankarDepartment of Pediatrics, Nippon Medical School, Tokyo, Japan.
Constantinos PitsiosMedical School, University of Cyprus, Nicosia, Cyprus.ORCID https://orcid.org/0000-0001-8935-278X
Todor A PopovClinic of Occupational Diseases, University Hospital Sveti Ivan Rilski, Sofia, Bulgaria.
Francesca PuggioniPersonalized Medicine, Allergy & Asthma, IRCCS Humanitas Research Hospital, Rozzano, Milan, Italy.
Santiago QuirceDepartment of Allergy, Hospital La Paz, Institute for Health Research (IdiPAZ), Madrid, Spain.ORCID https://orcid.org/0000-0001-8086-0921
Agné RamonaitéDepartment of Pulmonology and Allergology, Klaipeda National Hospital, Klaipeda, Lithuania.
Marysia RectoDivision of Adult and Pediatric Allergy and Immunology, University of the Philippines - Philippines General Hospital, Manila, Philippines.
Maria Susana Repka-RamirezDepartment of Allergy, Clinics Hospital, National University, San Lorenzo, Paraguay.ORCID https://orcid.org/0000-0002-9570-1277
Karla Robles-VelascoUniversidad Espíritu Santo, Samborondón, Ecuador.ORCID https://orcid.org/0000-0001-7780-1015
Menachem RottemDivision of Allergy, Asthma and Clinical Immunology, Emek Medical Center, Afula, Israel.
Marianella SalapatasARIA, Asthma, Rhinitis, Immunology & Allergy Department, Athens, Greece.
Joaquin SastreAllergy Service, Fundacion Jimenez Diaz, Autonoma University of Madrid, CIBERES-ISCIII, Madrid, Spain.ORCID https://orcid.org/0000-0003-4689-6837
Nicola ScichilonePROMISE Department, University of Palermo, Palermo, Italy.
Juan-Carlos SisulAllergy & Asthma, CLINICA SISUL, FACAAI, SPAAI, Asuncion, Paraguay.
Dirceu SoléDivision of Allergy, Clinical Immunology and Rheumatology, Department of Pediatrics, Federal University of São Paulo, São Paulo, Brazil.
Manuel Soto-MartinezDivision of Respiratory Medicine, Department of Pediatrics, Hospital Nacional de Niños, Universidad de Costa Rica, San Jose, Costa Rica.
Milan SovaDepartment of Respiratory Medicine and Tuberculosis, University Hospital, Brno, Czech Republic.
Katarina StevanovicInstitute of Allergology, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.
Pongsakorn TantilipikornDepartment of Otolaryngology, Faculty of Medicine Siriraj Hospital, Center of Research Excellence in Allergy & Immunology, Mahidol University, Bangkok, Thailand.
Ana Todo-BomImunoalergologia, Centro Hospitalar Universitário de Coimbra, Faculty of Medicine, University of Coimbra, Coimbra, Portugal.
Vladyslav TsarykDepartment of Clinical and Laboratory Immunology, Allergology and Medical Genetics, Bogomolets National Medical University, Kyiv, Ukraine.
Ioanna TsiligianniInternational Primary Care Respiratory Group IPCRG, Aberdeen, UK.
Marilyn Urrutia-PereiraFederal University of Pampa, Uruguaiana, Brazil.
Erkka ValovirtaDepartment of Lung Diseases and Clinical Immunology, University of Turku, Turku, Finland.
Tuula VasankariFiLHA, Finnish Lung Health Association, Helsinki, Finland.
Dana WallaceNova Southeastern University, College of Allopathic Medicine, Fort Lauderdale, Florida, USA.
Margitta WormDivision of Allergology and Immunology, Department Dermatology, Venerology and Allergology, Charité Universitätsmedizin Berlin, Berlin, Germany.ORCID https://orcid.org/0000-0002-3449-1245
Osman M YusufThe Allergy and Asthma Institute, Islamabad, Pakistan.
Fares ZaitounLebanese-American University, Clemenceau Medical Center DHCC, Dubai, UAE.
Mihaela ZidarnUniversity Clinic of Respiratory and Allergic Diseases, Golnik, Slovenia.
ARIA study group
Funding
No grant is acknowledged in the PubMed record.
Abstract
Allergic Rhinitis and its Impact on Asthma (ARIA) was, up until 2017, a guideline using the best evidence (Grading of Recommendations, Assessment, Development and Evaluation, GRADE) and developed as a change management strategy. A second change management strategy-in collaboration with the European Academy of Allergy and Clinical Immunology (ARIA-EAACI)-was developed as a person-centred, digitally enabled, artificial intelligence-assisted care (person-centred care) with strong political involvement. The digital tools of ARIA are mainly based on MASK-air, an Organisation for Economic Co-operation and Development (OECD) Best Practice for integrated care for chronic diseases. Artificial intelligence was used, in particular, to approach the patients' views and expectations. The current paper describes the steps to build and achieve a new change management strategy. The future of the Change Management strategy is (i) a collaboration between ARIA and EAACI, (ii) the development of ARIA 2024-2025 guidelines, (iii) the new ARIA-MeDALL classification of multimorbid airway diseases and (iv) embedding MASK-air in a registry for severe allergic diseases. The ultimate goals of the ARIA-EAACI change management strategy will be (i) the transformation of health and care in rhinitis and asthma multimorbidity and (ii) the development of novel guidelines and policies in a cost-effective manner, improving shared-decision-making.
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ARIAartificial intelligenceasthmamHealthrhinitis
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