Evidence map›Paper›PMID 42613521›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2026

NMR of Gangliosides.

Yoshiki Yamaguchi

Abstract read
PubMed Publisher
In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Yoshiki YamaguchiDivision of Structural Biology, Institute of Molecular Biomembrane and Glycobiology, Tohoku Medical and Pharmaceutical University, Sendai, Japan. yyoshiki@tohoku-mpu.ac.jp.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gangliosides influence numerous physiological functions through cell-surface interactions with exogenous and endogenous molecules. The importance of the glycan moiety of gangliosides has been demonstrated, and studies are underway to elucidate the mechanisms underlying their physiological functions, particularly with regard to structure-activity relationships. Nuclear magnetic resonance (NMR) spectroscopy provides unique insight into the chemical structure, conformation, dynamics, and interactions of biological samples at the atomic level. In this chapter, we outline protocols for NMR determination of the chemical structure of gangliosides, with a particular focus on identification of the sialic acid residues, and for analysis of protein-ganglioside interactions by saturation transfer difference NMR.

Indexed as

GangliosidesMagnetic Resonance SpectroscopyN-Acetylneuraminic AcidGangliosidesN-Acetylneuraminic AcidAnomericityChemical structureGlycosidic linkageGroup epitope mappingSaturation transfer difference (STD) NMRSialic acid

Identifiers

PMID42613521

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.