Evidence map›Paper›PMID 42613369›Full record

ArticleCellular & molecular immunology2026

Blocking the m

Chenbo Ding, Jiachen Zhao, Tian Zhao, Ye Xiao, Kai Li, Xiao Liu, Xuyang Ge, Demeng Qin, Zhiqian Huang, Yu Zhang and 9 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cellular & molecular immunology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Chenbo Ding *Institute for Immunology and Pathogenesis (IIP), Key Laboratory of Clinical Laboratory Diagnostics of Chinese Ministry of Education, Chongqing Medical University, Chongqing, China. chenbo.ding@cqmu.edu.cn.
Jiachen Zhao *Institute for Immunology and Pathogenesis (IIP), Key Laboratory of Clinical Laboratory Diagnostics of Chinese Ministry of Education, Chongqing Medical University, Chongqing, China.
Tian Zhao *Center for Immune-Related Diseases at Shanghai Institute of Immunology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Ye Xiao *Peking-Tsinghua Center for Life Sciences, Peking University, Beijing, China.
Kai Li *Peking-Tsinghua Center for Life Sciences, Peking University, Beijing, China.ORCID http://orcid.org/0009-0005-8796-8798
Xiao Liu *State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.
Xuyang GeInstitute for Immunology and Pathogenesis (IIP), Key Laboratory of Clinical Laboratory Diagnostics of Chinese Ministry of Education, Chongqing Medical University, Chongqing, China.
Demeng QinInstitute for Immunology and Pathogenesis (IIP), Key Laboratory of Clinical Laboratory Diagnostics of Chinese Ministry of Education, Chongqing Medical University, Chongqing, China.
Zhiqian HuangEye Institute and Department of Ophthalmology, Eye & ENT Hospital, Fudan University, Shanghai, China.
Yu ZhangInstitute for Immunology and Pathogenesis (IIP), Key Laboratory of Clinical Laboratory Diagnostics of Chinese Ministry of Education, Chongqing Medical University, Chongqing, China.
Hua LiuDepartment of Gastroenterology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shangha, China.
Zhiqing DiaoInstitute for Immunology and Pathogenesis (IIP), Key Laboratory of Clinical Laboratory Diagnostics of Chinese Ministry of Education, Chongqing Medical University, Chongqing, China.
Youqiong YeCenter for Immune-Related Diseases at Shanghai Institute of Immunology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.ORCID http://orcid.org/0000-0001-8332-4710
Richard A FlavellDepartment of Immunobiology, Yale University School of Medicine, New Haven, CT, USA.ORCID http://orcid.org/0000-0003-4461-0778
Cheng LuoState Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.ORCID http://orcid.org/0000-0003-3864-8382
Shijie ChenState Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China. sjchen@pharm.ecnu.edu.cn.
Chengqi YiPeking-Tsinghua Center for Life Sciences, Peking University, Beijing, China. chengqi.yi@pku.edu.cn.
Zhengting WangDepartment of Gastroenterology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shangha, China. zhengtingwang@shsmu.edu.cn.ORCID http://orcid.org/0000-0001-5533-5711
Hua-Bing LiInstitute for Immunology and Pathogenesis (IIP), Key Laboratory of Clinical Laboratory Diagnostics of Chinese Ministry of Education, Chongqing Medical University, Chongqing, China. huabing.li@shsmu.edu.cn.ORCID http://orcid.org/0000-0003-3573-6803

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Macrophage-enteric neuron dialog is crucial for intestinal homeostasis, but its specific role and underlying mechanism in inflammatory bowel disease (IBD) pathogenesis remain elusive. Here, we demonstrate that colonic macrophage-mediated extracellular matrix (ECM) remodeling orchestrates enteric neuronal maturation and dictates colitis progression. The depletion of Pcif1, recognized as a unique methyltransferase for m

Indexed as

ColitisMacrophagesMethyltransferasesNeuronsAnimalsDisease ProgressionExtracellular MatrixHumansMiceMice, Inbred C57BLRNA MethylationMethyltransferasesEnteric neuronExtracellular matrixInflammatory bowel diseaseMacrophagePcif1

Identifiers

PMID42613369
PMCPMC13623923

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.