Evidence map›Paper›PMID 42613185›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2026

Corticolimbic Structure-Function Coupling Is Sensitive to Childhood Adversity and Buffers Adversity-Related Symptoms during Development.

Lucinda M Sisk, Taylor J Keding, Allison Drew, Emilie Ma, Golia Shafiei, Matthew Cieslak, Theodore D Satterthwaite, Dylan G Gee

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Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Lucinda M SiskDepartment of Psychology, Yale University, New Haven, Connecticut 06510 lucinda.sisk@pennmedicine.upenn.edu dylan.gee@yale.edu.ORCID https://orcid.org/0000-0003-4900-9770
Taylor J KedingDepartment of Psychology, Yale University, New Haven, Connecticut 06510.
Allison DrewDepartment of Psychology, Yale University, New Haven, Connecticut 06510.
Emilie MaDepartment of Psychology, Yale University, New Haven, Connecticut 06510.
Golia ShafieiPenn Lifespan Informatics and Neuroimaging Center (PennLINC), Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104.
Matthew CieslakPenn Lifespan Informatics and Neuroimaging Center (PennLINC), Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104.
Theodore D SatterthwaitePenn Lifespan Informatics and Neuroimaging Center (PennLINC), Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104.
Dylan G GeeDepartment of Psychology, Yale University, New Haven, Connecticut 06510 lucinda.sisk@pennmedicine.upenn.edu dylan.gee@yale.edu.ORCID https://orcid.org/0000-0002-3685-2710

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Childhood adversity is a potent predictor of mental health problems across the lifespan, and cross-species literature implicates stress-sensitive corticolimbic circuits in adversity-related psychopathology. Structure-function coupling (SFC) is a multimodal marker that is sensitive to developmental plasticity. While emerging evidence suggests cortical SFC is sensitive to adversity exposure during early childhood, it is unknown how SFC in stress-sensitive corticolimbic circuits links adversity exposure with mental health across development. We examined associations between adversity exposure, transdiagnostic symptomatology, and both amygdala-cortical and hippocampal-cortical SFC across development in a large youth sample (

Indexed as

Adverse Childhood ExperiencesAmygdalaCerebral CortexLimbic SystemStress, PsychologicalAdolescentChildFemaleHippocampusHumansMagnetic Resonance ImagingMaleNeural PathwaysPrefrontal Cortexadversitydevelopmentneuroplasticityresiliencestressstructure–function coupling

Identifiers

PMID42613185
PMCPMC13583330

What OpenQuestion holds

Textmetadata
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.